{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2012:V3M4VPHKK2GP5GZVKDHUNYKVT2","short_pith_number":"pith:V3M4VPHK","canonical_record":{"source":{"id":"1206.4087","kind":"arxiv","version":2},"metadata":{"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"q-bio.BM","submitted_at":"2012-06-18T22:02:35Z","cross_cats_sorted":[],"title_canon_sha256":"26905e8e58fb018a086c41a16848de8caf4c0917dba1ef16cb5aae53d3e4725e","abstract_canon_sha256":"6d64b3ec1333c5f1bcc85825d9196286b39cf33c29a54c49c7afc6302c32e40f"},"schema_version":"1.0"},"canonical_sha256":"aed9cabcea568cfe9b3550cf46e1559ea29f3ffd011b7f90b455a62b23580d22","source":{"kind":"arxiv","id":"1206.4087","version":2},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1206.4087","created_at":"2026-05-18T01:22:03Z"},{"alias_kind":"arxiv_version","alias_value":"1206.4087v2","created_at":"2026-05-18T01:22:03Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1206.4087","created_at":"2026-05-18T01:22:03Z"},{"alias_kind":"pith_short_12","alias_value":"V3M4VPHKK2GP","created_at":"2026-05-18T12:27:25Z"},{"alias_kind":"pith_short_16","alias_value":"V3M4VPHKK2GP5GZV","created_at":"2026-05-18T12:27:25Z"},{"alias_kind":"pith_short_8","alias_value":"V3M4VPHK","created_at":"2026-05-18T12:27:25Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2012:V3M4VPHKK2GP5GZVKDHUNYKVT2","target":"record","payload":{"canonical_record":{"source":{"id":"1206.4087","kind":"arxiv","version":2},"metadata":{"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"q-bio.BM","submitted_at":"2012-06-18T22:02:35Z","cross_cats_sorted":[],"title_canon_sha256":"26905e8e58fb018a086c41a16848de8caf4c0917dba1ef16cb5aae53d3e4725e","abstract_canon_sha256":"6d64b3ec1333c5f1bcc85825d9196286b39cf33c29a54c49c7afc6302c32e40f"},"schema_version":"1.0"},"canonical_sha256":"aed9cabcea568cfe9b3550cf46e1559ea29f3ffd011b7f90b455a62b23580d22","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T01:22:03.610287Z","signature_b64":"kXjpQ+Fl/gvMbbo9n/3/+0t2+tFoeiqne/5SzWx/oJnenWZSB76/cWggwdRlI4b8aFJKr+CE3SJrn8XIbgCVAg==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"aed9cabcea568cfe9b3550cf46e1559ea29f3ffd011b7f90b455a62b23580d22","last_reissued_at":"2026-05-18T01:22:03.609725Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T01:22:03.609725Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1206.4087","source_version":2,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:22:03Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"+TJALOEOHydKWD6tlJkXEVNFdCYvBozVcCidtv2Scl0TIonF1SdJChe1cNxOEwtRr+xkZ+oP3wQLz+3aHjj5Bg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-25T13:13:05.201588Z"},"content_sha256":"95df8cea8e998a14af9eefa1c114705992aa66a4766d9962f87b78ae0609d34e","schema_version":"1.0","event_id":"sha256:95df8cea8e998a14af9eefa1c114705992aa66a4766d9962f87b78ae0609d34e"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2012:V3M4VPHKK2GP5GZVKDHUNYKVT2","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Studying RNA homology and conservation with Infernal: from single sequences to RNA families","license":"http://creativecommons.org/licenses/by/4.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.BM","authors_text":"Lars Barquist, Paul P. Gardner, Sarah W. Burge","submitted_at":"2012-06-18T22:02:35Z","abstract_excerpt":"Emerging high-throughput technologies have led to a deluge of putative non-coding RNA (ncRNA) sequences identified in a wide variety of organisms. Systematic characterization of these transcripts will be a tremendous challenge. Homology detection is critical to making maximal use of functional information gathered about ncRNAs: identifying homologous sequence allows us to transfer information gathered in one organism to another quickly and with a high degree of confidence. ncRNA presents a challenge for homology detection, as the primary sequence is often poorly conserved and de novo secondary"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1206.4087","kind":"arxiv","version":2},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:22:03Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"oLnp3maJk2Eia2G4jj0iYjddUh0NfVE1hTPr00urmPktN2Jc+qmI+fjl5ejBSVHaumYxbLtlIl3KXDLIw5XZBA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-25T13:13:05.201933Z"},"content_sha256":"702cfac5be4b67127a3155100cc7db7282750ee8232b1af35d8af68678ca5286","schema_version":"1.0","event_id":"sha256:702cfac5be4b67127a3155100cc7db7282750ee8232b1af35d8af68678ca5286"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/V3M4VPHKK2GP5GZVKDHUNYKVT2/bundle.json","state_url":"https://pith.science/pith/V3M4VPHKK2GP5GZVKDHUNYKVT2/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/V3M4VPHKK2GP5GZVKDHUNYKVT2/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-25T13:13:05Z","links":{"resolver":"https://pith.science/pith/V3M4VPHKK2GP5GZVKDHUNYKVT2","bundle":"https://pith.science/pith/V3M4VPHKK2GP5GZVKDHUNYKVT2/bundle.json","state":"https://pith.science/pith/V3M4VPHKK2GP5GZVKDHUNYKVT2/state.json","well_known_bundle":"https://pith.science/.well-known/pith/V3M4VPHKK2GP5GZVKDHUNYKVT2/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2012:V3M4VPHKK2GP5GZVKDHUNYKVT2","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"6d64b3ec1333c5f1bcc85825d9196286b39cf33c29a54c49c7afc6302c32e40f","cross_cats_sorted":[],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"q-bio.BM","submitted_at":"2012-06-18T22:02:35Z","title_canon_sha256":"26905e8e58fb018a086c41a16848de8caf4c0917dba1ef16cb5aae53d3e4725e"},"schema_version":"1.0","source":{"id":"1206.4087","kind":"arxiv","version":2}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1206.4087","created_at":"2026-05-18T01:22:03Z"},{"alias_kind":"arxiv_version","alias_value":"1206.4087v2","created_at":"2026-05-18T01:22:03Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1206.4087","created_at":"2026-05-18T01:22:03Z"},{"alias_kind":"pith_short_12","alias_value":"V3M4VPHKK2GP","created_at":"2026-05-18T12:27:25Z"},{"alias_kind":"pith_short_16","alias_value":"V3M4VPHKK2GP5GZV","created_at":"2026-05-18T12:27:25Z"},{"alias_kind":"pith_short_8","alias_value":"V3M4VPHK","created_at":"2026-05-18T12:27:25Z"}],"graph_snapshots":[{"event_id":"sha256:702cfac5be4b67127a3155100cc7db7282750ee8232b1af35d8af68678ca5286","target":"graph","created_at":"2026-05-18T01:22:03Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Emerging high-throughput technologies have led to a deluge of putative non-coding RNA (ncRNA) sequences identified in a wide variety of organisms. Systematic characterization of these transcripts will be a tremendous challenge. Homology detection is critical to making maximal use of functional information gathered about ncRNAs: identifying homologous sequence allows us to transfer information gathered in one organism to another quickly and with a high degree of confidence. ncRNA presents a challenge for homology detection, as the primary sequence is often poorly conserved and de novo secondary","authors_text":"Lars Barquist, Paul P. Gardner, Sarah W. Burge","cross_cats":[],"headline":"","license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"q-bio.BM","submitted_at":"2012-06-18T22:02:35Z","title":"Studying RNA homology and conservation with Infernal: from single sequences to RNA families"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1206.4087","kind":"arxiv","version":2},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:95df8cea8e998a14af9eefa1c114705992aa66a4766d9962f87b78ae0609d34e","target":"record","created_at":"2026-05-18T01:22:03Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"6d64b3ec1333c5f1bcc85825d9196286b39cf33c29a54c49c7afc6302c32e40f","cross_cats_sorted":[],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"q-bio.BM","submitted_at":"2012-06-18T22:02:35Z","title_canon_sha256":"26905e8e58fb018a086c41a16848de8caf4c0917dba1ef16cb5aae53d3e4725e"},"schema_version":"1.0","source":{"id":"1206.4087","kind":"arxiv","version":2}},"canonical_sha256":"aed9cabcea568cfe9b3550cf46e1559ea29f3ffd011b7f90b455a62b23580d22","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"aed9cabcea568cfe9b3550cf46e1559ea29f3ffd011b7f90b455a62b23580d22","first_computed_at":"2026-05-18T01:22:03.609725Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T01:22:03.609725Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"kXjpQ+Fl/gvMbbo9n/3/+0t2+tFoeiqne/5SzWx/oJnenWZSB76/cWggwdRlI4b8aFJKr+CE3SJrn8XIbgCVAg==","signature_status":"signed_v1","signed_at":"2026-05-18T01:22:03.610287Z","signed_message":"canonical_sha256_bytes"},"source_id":"1206.4087","source_kind":"arxiv","source_version":2}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:95df8cea8e998a14af9eefa1c114705992aa66a4766d9962f87b78ae0609d34e","sha256:702cfac5be4b67127a3155100cc7db7282750ee8232b1af35d8af68678ca5286"],"state_sha256":"692a917c707f403729250ff5691dc7b8bd42e9bae7e07e7c8fdeec6d59b2587d"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"/dK1SHU3J+yeh78ypLVZ9xK62jkm4xuw4JTQ1V4rdp3scmFA6Nkz/DCSv3HxeifHvGFwJrklbNyT9NtQf9UKDg==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-25T13:13:05.203903Z","bundle_sha256":"36c23e01cda0cf3711fd47ef9c8f6f1a1ae9d6c0ba6d26bc456dc408349b2db3"}}