{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2019:VQSXF2BLPJ6WNEKPJ57OBBGSYS","short_pith_number":"pith:VQSXF2BL","canonical_record":{"source":{"id":"1902.10589","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.CB","submitted_at":"2019-02-27T15:29:30Z","cross_cats_sorted":["physics.bio-ph","q-bio.QM"],"title_canon_sha256":"6d986196542b24343fe7b1dfc66034db1c099e70e6e78eecfbd298f5294a4810","abstract_canon_sha256":"45a071ef17df472430c7e48d0abf2658a023970b78aa5942b131a18b0f9a2b41"},"schema_version":"1.0"},"canonical_sha256":"ac2572e82b7a7d66914f4f7ee084d2c4a95c36ca004b83fe55d80ba9efb2a4a2","source":{"kind":"arxiv","id":"1902.10589","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1902.10589","created_at":"2026-05-17T23:52:30Z"},{"alias_kind":"arxiv_version","alias_value":"1902.10589v1","created_at":"2026-05-17T23:52:30Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1902.10589","created_at":"2026-05-17T23:52:30Z"},{"alias_kind":"pith_short_12","alias_value":"VQSXF2BLPJ6W","created_at":"2026-05-18T12:33:30Z"},{"alias_kind":"pith_short_16","alias_value":"VQSXF2BLPJ6WNEKP","created_at":"2026-05-18T12:33:30Z"},{"alias_kind":"pith_short_8","alias_value":"VQSXF2BL","created_at":"2026-05-18T12:33:30Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2019:VQSXF2BLPJ6WNEKPJ57OBBGSYS","target":"record","payload":{"canonical_record":{"source":{"id":"1902.10589","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.CB","submitted_at":"2019-02-27T15:29:30Z","cross_cats_sorted":["physics.bio-ph","q-bio.QM"],"title_canon_sha256":"6d986196542b24343fe7b1dfc66034db1c099e70e6e78eecfbd298f5294a4810","abstract_canon_sha256":"45a071ef17df472430c7e48d0abf2658a023970b78aa5942b131a18b0f9a2b41"},"schema_version":"1.0"},"canonical_sha256":"ac2572e82b7a7d66914f4f7ee084d2c4a95c36ca004b83fe55d80ba9efb2a4a2","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-17T23:52:30.432930Z","signature_b64":"tIG/VogRznKBRJabr89vaeTl6jSf5QkdARmEgKQyJ8ulSYC06OFzJd1XnAb3dPI0ShE59dC0Nda34Yu8PnrACQ==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"ac2572e82b7a7d66914f4f7ee084d2c4a95c36ca004b83fe55d80ba9efb2a4a2","last_reissued_at":"2026-05-17T23:52:30.432455Z","signature_status":"signed_v1","first_computed_at":"2026-05-17T23:52:30.432455Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1902.10589","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-17T23:52:30Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"ftptCiRI18R7laisSdAQXINyzMoSpQL3GsUbfA3PC7lBOwvXdu6OOjiGwcOwzLO5fUplZtvEJCUvLaPUxeDuDQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-27T06:49:56.703539Z"},"content_sha256":"4e853c010bb6a9f5780e901b160431cbd13ee5c966f0fa8f713d83121410e53c","schema_version":"1.0","event_id":"sha256:4e853c010bb6a9f5780e901b160431cbd13ee5c966f0fa8f713d83121410e53c"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2019:VQSXF2BLPJ6WNEKPJ57OBBGSYS","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Principles of efficient chemotactic pursuit","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["physics.bio-ph","q-bio.QM"],"primary_cat":"q-bio.CB","authors_text":"Claus Metzner","submitted_at":"2019-02-27T15:29:30Z","abstract_excerpt":"In chemotaxis, cells are modulating their migration patterns in response to concentration gradients of a guiding substance. Immune cells are believed to use such chemotactic sensing for remotely detecting and homing in on pathogens. Considering that an immune cells may encounter a multitude of targets with vastly different migration properties, ranging from immobile to highly mobile, it is not clear which strategies of chemotactic pursuit are simultaneously efficient and versatile. We takle this problem theoretically and define a tunable response function that maps temporal or spatial concentr"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1902.10589","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-17T23:52:30Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"B3Sm8mghL9ak6f7XI2bhAiOzlgvcF2HcHrBaooB+uOu5+mSHLXFALlpe3v8ggyA8O3/OrC31C+okevQ/KkHbAw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-27T06:49:56.704220Z"},"content_sha256":"f3c0f1a6c34d3d3801898dd2407800f8db2eeb542c68029742e29e82aaa76965","schema_version":"1.0","event_id":"sha256:f3c0f1a6c34d3d3801898dd2407800f8db2eeb542c68029742e29e82aaa76965"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/VQSXF2BLPJ6WNEKPJ57OBBGSYS/bundle.json","state_url":"https://pith.science/pith/VQSXF2BLPJ6WNEKPJ57OBBGSYS/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/VQSXF2BLPJ6WNEKPJ57OBBGSYS/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-05-27T06:49:56Z","links":{"resolver":"https://pith.science/pith/VQSXF2BLPJ6WNEKPJ57OBBGSYS","bundle":"https://pith.science/pith/VQSXF2BLPJ6WNEKPJ57OBBGSYS/bundle.json","state":"https://pith.science/pith/VQSXF2BLPJ6WNEKPJ57OBBGSYS/state.json","well_known_bundle":"https://pith.science/.well-known/pith/VQSXF2BLPJ6WNEKPJ57OBBGSYS/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2019:VQSXF2BLPJ6WNEKPJ57OBBGSYS","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"45a071ef17df472430c7e48d0abf2658a023970b78aa5942b131a18b0f9a2b41","cross_cats_sorted":["physics.bio-ph","q-bio.QM"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.CB","submitted_at":"2019-02-27T15:29:30Z","title_canon_sha256":"6d986196542b24343fe7b1dfc66034db1c099e70e6e78eecfbd298f5294a4810"},"schema_version":"1.0","source":{"id":"1902.10589","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1902.10589","created_at":"2026-05-17T23:52:30Z"},{"alias_kind":"arxiv_version","alias_value":"1902.10589v1","created_at":"2026-05-17T23:52:30Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1902.10589","created_at":"2026-05-17T23:52:30Z"},{"alias_kind":"pith_short_12","alias_value":"VQSXF2BLPJ6W","created_at":"2026-05-18T12:33:30Z"},{"alias_kind":"pith_short_16","alias_value":"VQSXF2BLPJ6WNEKP","created_at":"2026-05-18T12:33:30Z"},{"alias_kind":"pith_short_8","alias_value":"VQSXF2BL","created_at":"2026-05-18T12:33:30Z"}],"graph_snapshots":[{"event_id":"sha256:f3c0f1a6c34d3d3801898dd2407800f8db2eeb542c68029742e29e82aaa76965","target":"graph","created_at":"2026-05-17T23:52:30Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"In chemotaxis, cells are modulating their migration patterns in response to concentration gradients of a guiding substance. Immune cells are believed to use such chemotactic sensing for remotely detecting and homing in on pathogens. Considering that an immune cells may encounter a multitude of targets with vastly different migration properties, ranging from immobile to highly mobile, it is not clear which strategies of chemotactic pursuit are simultaneously efficient and versatile. We takle this problem theoretically and define a tunable response function that maps temporal or spatial concentr","authors_text":"Claus Metzner","cross_cats":["physics.bio-ph","q-bio.QM"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.CB","submitted_at":"2019-02-27T15:29:30Z","title":"Principles of efficient chemotactic pursuit"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1902.10589","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:4e853c010bb6a9f5780e901b160431cbd13ee5c966f0fa8f713d83121410e53c","target":"record","created_at":"2026-05-17T23:52:30Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"45a071ef17df472430c7e48d0abf2658a023970b78aa5942b131a18b0f9a2b41","cross_cats_sorted":["physics.bio-ph","q-bio.QM"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.CB","submitted_at":"2019-02-27T15:29:30Z","title_canon_sha256":"6d986196542b24343fe7b1dfc66034db1c099e70e6e78eecfbd298f5294a4810"},"schema_version":"1.0","source":{"id":"1902.10589","kind":"arxiv","version":1}},"canonical_sha256":"ac2572e82b7a7d66914f4f7ee084d2c4a95c36ca004b83fe55d80ba9efb2a4a2","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"ac2572e82b7a7d66914f4f7ee084d2c4a95c36ca004b83fe55d80ba9efb2a4a2","first_computed_at":"2026-05-17T23:52:30.432455Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-17T23:52:30.432455Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"tIG/VogRznKBRJabr89vaeTl6jSf5QkdARmEgKQyJ8ulSYC06OFzJd1XnAb3dPI0ShE59dC0Nda34Yu8PnrACQ==","signature_status":"signed_v1","signed_at":"2026-05-17T23:52:30.432930Z","signed_message":"canonical_sha256_bytes"},"source_id":"1902.10589","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:4e853c010bb6a9f5780e901b160431cbd13ee5c966f0fa8f713d83121410e53c","sha256:f3c0f1a6c34d3d3801898dd2407800f8db2eeb542c68029742e29e82aaa76965"],"state_sha256":"b4f287f4113b8ea425b6593332c27296cb032106fdfa553c3504a04b4e8b14b6"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"7IOHtPhDMT3haftxDt3/q8YlCUS9/SlFXcCkFGM88XmkI7QPy5qXFFCVDxbmJ//8AFxtNn0R27X5ew18qjDCAQ==","signed_message":"bundle_sha256_bytes","signed_at":"2026-05-27T06:49:56.706790Z","bundle_sha256":"f88fb6b3a3d6241b98ddfb27c6db3f0eaee4ab294ae614840d9f803cf914b49f"}}