{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2025:VSHPOGKHXKV5UZYNN5NB5VPG5W","short_pith_number":"pith:VSHPOGKH","canonical_record":{"source":{"id":"2507.02379","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"cs.AI","submitted_at":"2025-07-03T07:21:19Z","cross_cats_sorted":["q-bio.BM"],"title_canon_sha256":"e6862ee41ccd61f233fc543dbd3c599212eeeb952f0d1e6a72e234d6656cd21b","abstract_canon_sha256":"208ab9183794e86805084b32567a66fa3146470b23ed2c3797fa183175bf34e1"},"schema_version":"1.0"},"canonical_sha256":"ac8ef71947baabda670d6f5a1ed5e6ed9fe440a5f3c8921e63a63c2e2cf97213","source":{"kind":"arxiv","id":"2507.02379","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2507.02379","created_at":"2026-07-05T11:31:17Z"},{"alias_kind":"arxiv_version","alias_value":"2507.02379v1","created_at":"2026-07-05T11:31:17Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2507.02379","created_at":"2026-07-05T11:31:17Z"},{"alias_kind":"pith_short_12","alias_value":"VSHPOGKHXKV5","created_at":"2026-07-05T11:31:17Z"},{"alias_kind":"pith_short_16","alias_value":"VSHPOGKHXKV5UZYN","created_at":"2026-07-05T11:31:17Z"},{"alias_kind":"pith_short_8","alias_value":"VSHPOGKH","created_at":"2026-07-05T11:31:17Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2025:VSHPOGKHXKV5UZYNN5NB5VPG5W","target":"record","payload":{"canonical_record":{"source":{"id":"2507.02379","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"cs.AI","submitted_at":"2025-07-03T07:21:19Z","cross_cats_sorted":["q-bio.BM"],"title_canon_sha256":"e6862ee41ccd61f233fc543dbd3c599212eeeb952f0d1e6a72e234d6656cd21b","abstract_canon_sha256":"208ab9183794e86805084b32567a66fa3146470b23ed2c3797fa183175bf34e1"},"schema_version":"1.0"},"canonical_sha256":"ac8ef71947baabda670d6f5a1ed5e6ed9fe440a5f3c8921e63a63c2e2cf97213","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T11:31:17.206099Z","signature_b64":"dNW4ftX29Ds1IfpxO2+erA2qM8l27X/i36xw2lfTUiArO8hoGa64RRNE6i8Xu8KyaofWT3x3tIq61Ifaf1sRBQ==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"ac8ef71947baabda670d6f5a1ed5e6ed9fe440a5f3c8921e63a63c2e2cf97213","last_reissued_at":"2026-07-05T11:31:17.205579Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T11:31:17.205579Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2507.02379","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T11:31:17Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"xe4+vv2x8fOyK4eku1HLnOH0OQuRpLJSsVfCSKBIU6pF/dDvY1Y3tJ+k+TU4QkEtkBsUqH1O8ISFUW1DJ692BA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-14T16:58:44.855983Z"},"content_sha256":"fe68b41f0da74584e34a843b0220768553f5749583859318fc5e14b0161559c0","schema_version":"1.0","event_id":"sha256:fe68b41f0da74584e34a843b0220768553f5749583859318fc5e14b0161559c0"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2025:VSHPOGKHXKV5UZYNN5NB5VPG5W","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"An AI-native experimental laboratory for autonomous biomolecular engineering","license":"http://creativecommons.org/licenses/by/4.0/","headline":"","cross_cats":["q-bio.BM"],"primary_cat":"cs.AI","authors_text":"Chunhai Fan, Fei Wang, Haibo Chen, Jiabin Wang, Jingkai Yang, Lei Zhao, Mingqiang Li, Mingyu Wu, Qingting Li, Tianyu Huang, Zhaoguo Wang, Zhiyuan Dong","submitted_at":"2025-07-03T07:21:19Z","abstract_excerpt":"Autonomous scientific research, capable of independently conducting complex experiments and serving non-specialists, represents a long-held aspiration. Achieving it requires a fundamental paradigm shift driven by artificial intelligence (AI). While autonomous experimental systems are emerging, they remain confined to areas featuring singular objectives and well-defined, simple experimental workflows, such as chemical synthesis and catalysis. We present an AI-native autonomous laboratory, targeting highly complex scientific experiments for applications like autonomous biomolecular engineering. "},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2507.02379","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2507.02379/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T11:31:17Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"w6wtoKHb9IGh+4L4xfvMltw7LtGGl8aUkhjDUFFNn+GjFKECnh2NhqJg9BVrWNHqjAq2+3osyb98QQkC5CobBA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-14T16:58:44.856966Z"},"content_sha256":"935dccaa1790c4c27320acd7bf46f07e03730dc6b9ceccc409ddaebea2a4a472","schema_version":"1.0","event_id":"sha256:935dccaa1790c4c27320acd7bf46f07e03730dc6b9ceccc409ddaebea2a4a472"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/VSHPOGKHXKV5UZYNN5NB5VPG5W/bundle.json","state_url":"https://pith.science/pith/VSHPOGKHXKV5UZYNN5NB5VPG5W/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/VSHPOGKHXKV5UZYNN5NB5VPG5W/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-08-14T16:58:44Z","links":{"resolver":"https://pith.science/pith/VSHPOGKHXKV5UZYNN5NB5VPG5W","bundle":"https://pith.science/pith/VSHPOGKHXKV5UZYNN5NB5VPG5W/bundle.json","state":"https://pith.science/pith/VSHPOGKHXKV5UZYNN5NB5VPG5W/state.json","well_known_bundle":"https://pith.science/.well-known/pith/VSHPOGKHXKV5UZYNN5NB5VPG5W/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2025:VSHPOGKHXKV5UZYNN5NB5VPG5W","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"208ab9183794e86805084b32567a66fa3146470b23ed2c3797fa183175bf34e1","cross_cats_sorted":["q-bio.BM"],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"cs.AI","submitted_at":"2025-07-03T07:21:19Z","title_canon_sha256":"e6862ee41ccd61f233fc543dbd3c599212eeeb952f0d1e6a72e234d6656cd21b"},"schema_version":"1.0","source":{"id":"2507.02379","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2507.02379","created_at":"2026-07-05T11:31:17Z"},{"alias_kind":"arxiv_version","alias_value":"2507.02379v1","created_at":"2026-07-05T11:31:17Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2507.02379","created_at":"2026-07-05T11:31:17Z"},{"alias_kind":"pith_short_12","alias_value":"VSHPOGKHXKV5","created_at":"2026-07-05T11:31:17Z"},{"alias_kind":"pith_short_16","alias_value":"VSHPOGKHXKV5UZYN","created_at":"2026-07-05T11:31:17Z"},{"alias_kind":"pith_short_8","alias_value":"VSHPOGKH","created_at":"2026-07-05T11:31:17Z"}],"graph_snapshots":[{"event_id":"sha256:935dccaa1790c4c27320acd7bf46f07e03730dc6b9ceccc409ddaebea2a4a472","target":"graph","created_at":"2026-07-05T11:31:17Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2507.02379/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Autonomous scientific research, capable of independently conducting complex experiments and serving non-specialists, represents a long-held aspiration. Achieving it requires a fundamental paradigm shift driven by artificial intelligence (AI). While autonomous experimental systems are emerging, they remain confined to areas featuring singular objectives and well-defined, simple experimental workflows, such as chemical synthesis and catalysis. We present an AI-native autonomous laboratory, targeting highly complex scientific experiments for applications like autonomous biomolecular engineering. ","authors_text":"Chunhai Fan, Fei Wang, Haibo Chen, Jiabin Wang, Jingkai Yang, Lei Zhao, Mingqiang Li, Mingyu Wu, Qingting Li, Tianyu Huang, Zhaoguo Wang, Zhiyuan Dong","cross_cats":["q-bio.BM"],"headline":"","license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"cs.AI","submitted_at":"2025-07-03T07:21:19Z","title":"An AI-native experimental laboratory for autonomous biomolecular engineering"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2507.02379","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:fe68b41f0da74584e34a843b0220768553f5749583859318fc5e14b0161559c0","target":"record","created_at":"2026-07-05T11:31:17Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"208ab9183794e86805084b32567a66fa3146470b23ed2c3797fa183175bf34e1","cross_cats_sorted":["q-bio.BM"],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"cs.AI","submitted_at":"2025-07-03T07:21:19Z","title_canon_sha256":"e6862ee41ccd61f233fc543dbd3c599212eeeb952f0d1e6a72e234d6656cd21b"},"schema_version":"1.0","source":{"id":"2507.02379","kind":"arxiv","version":1}},"canonical_sha256":"ac8ef71947baabda670d6f5a1ed5e6ed9fe440a5f3c8921e63a63c2e2cf97213","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"ac8ef71947baabda670d6f5a1ed5e6ed9fe440a5f3c8921e63a63c2e2cf97213","first_computed_at":"2026-07-05T11:31:17.205579Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T11:31:17.205579Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"dNW4ftX29Ds1IfpxO2+erA2qM8l27X/i36xw2lfTUiArO8hoGa64RRNE6i8Xu8KyaofWT3x3tIq61Ifaf1sRBQ==","signature_status":"signed_v1","signed_at":"2026-07-05T11:31:17.206099Z","signed_message":"canonical_sha256_bytes"},"source_id":"2507.02379","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:fe68b41f0da74584e34a843b0220768553f5749583859318fc5e14b0161559c0","sha256:935dccaa1790c4c27320acd7bf46f07e03730dc6b9ceccc409ddaebea2a4a472"],"state_sha256":"c4be265fcfc7e9167bfebf2ee91514ab9430550f4bf697a3d00d5bc1476af1e3"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"ylThkk/9IfN3D8IotDuclugXdYDhPEZORWMfOtyy07EeSy0q2Jj22oq1YqC+NsSPdciQm0N2lF5DFx4LKdR5Cg==","signed_message":"bundle_sha256_bytes","signed_at":"2026-08-14T16:58:44.863751Z","bundle_sha256":"d76bce669e387c4bf5c0a2b69ffaa0dafaf26d14d234e9393bc383c5ad5bb9e2"}}