{"record_type":"pith_number_record","schema_url":"https://pith.science/schemas/pith-number/v1.json","pith_number":"pith:2026:VVNM2PMZGPKE6OBEK7HIOZI75C","short_pith_number":"pith:VVNM2PMZ","schema_version":"1.0","canonical_sha256":"ad5acd3d9933d44f382457ce87651fe8ac3a683860f639ea7027820615de0da6","source":{"kind":"arxiv","id":"2607.24503","version":1},"attestation_state":"computed","paper":{"title":"Synaptic clustering emerges from learning and supports covariance discrimination","license":"http://creativecommons.org/licenses/by/4.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.NC","authors_text":"Bernardo Sabatini, Elom Amematsro, Houman Safaai, Ilenna Simone Jones, Maceo Richards","submitted_at":"2026-07-27T14:36:51Z","abstract_excerpt":"Functional synapse clusters (FSCs) are synapses with correlated presynaptic activity that are colocalized on the same neuronal dendritic branch. FSCs have been observed after learning in cortical and hippocampal pyramidal neurons. However, previous efforts to ablate FSCs by pharmacologically blocking dendritic nonlinearities to establish causal necessity may have confounded effects. Therefore, whether FSCs are causally necessary for computation is unknown. Here, we attempt to isolate FSCs from this potential confounder in silico. We train Dendrinet, an artificial neural network architecture wi"},"verification_status":{"content_addressed":true,"pith_receipt":true,"author_attested":false,"weak_author_claims":0,"strong_author_claims":0,"externally_anchored":false,"storage_verified":false,"citation_signatures":0,"replication_records":0,"graph_snapshot":true,"references_resolved":false,"formal_links_present":false},"canonical_record":{"source":{"id":"2607.24503","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"q-bio.NC","submitted_at":"2026-07-27T14:36:51Z","cross_cats_sorted":[],"title_canon_sha256":"076a99dd177743fa604c5933d2d0aa9153c8328ab4a77ef1b7bda69b35647274","abstract_canon_sha256":"5fd6b3b6e92858021557ecee9d67efe1986484222e75f6c89d833b4e6553225c"},"schema_version":"1.0"},"receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-28T02:24:06.925674Z","signature_b64":"Hji5AWK61JblX41ZPh/4TzvudFvaFCiO12dbdzrI0rgqozoSIPVNfCBhKT6qt1Wov1KCRm4EsgW4rrxJd782DQ==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"ad5acd3d9933d44f382457ce87651fe8ac3a683860f639ea7027820615de0da6","last_reissued_at":"2026-07-28T02:24:06.924863Z","signature_status":"signed_v1","first_computed_at":"2026-07-28T02:24:06.924863Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"graph_snapshot":{"paper":{"title":"Synaptic clustering emerges from learning and supports covariance discrimination","license":"http://creativecommons.org/licenses/by/4.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.NC","authors_text":"Bernardo Sabatini, Elom Amematsro, Houman Safaai, Ilenna Simone Jones, Maceo Richards","submitted_at":"2026-07-27T14:36:51Z","abstract_excerpt":"Functional synapse clusters (FSCs) are synapses with correlated presynaptic activity that are colocalized on the same neuronal dendritic branch. FSCs have been observed after learning in cortical and hippocampal pyramidal neurons. However, previous efforts to ablate FSCs by pharmacologically blocking dendritic nonlinearities to establish causal necessity may have confounded effects. Therefore, whether FSCs are causally necessary for computation is unknown. Here, we attempt to isolate FSCs from this potential confounder in silico. We train Dendrinet, an artificial neural network architecture wi"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2607.24503","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2607.24503/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"aliases":[{"alias_kind":"arxiv","alias_value":"2607.24503","created_at":"2026-07-28T02:24:06.925261+00:00"},{"alias_kind":"arxiv_version","alias_value":"2607.24503v1","created_at":"2026-07-28T02:24:06.925261+00:00"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2607.24503","created_at":"2026-07-28T02:24:06.925261+00:00"},{"alias_kind":"pith_short_12","alias_value":"VVNM2PMZGPKE","created_at":"2026-07-28T02:24:06.925261+00:00"},{"alias_kind":"pith_short_16","alias_value":"VVNM2PMZGPKE6OBE","created_at":"2026-07-28T02:24:06.925261+00:00"},{"alias_kind":"pith_short_8","alias_value":"VVNM2PMZ","created_at":"2026-07-28T02:24:06.925261+00:00"}],"events":[],"event_summary":{},"paper_claims":[],"inbound_citations":{"count":0,"internal_anchor_count":0,"sample":[]},"formal_canon":{"evidence_count":0,"sample":[],"anchors":[]},"links":{"html":"https://pith.science/pith/VVNM2PMZGPKE6OBEK7HIOZI75C","json":"https://pith.science/pith/VVNM2PMZGPKE6OBEK7HIOZI75C.json","graph_json":"https://pith.science/api/pith-number/VVNM2PMZGPKE6OBEK7HIOZI75C/graph.json","events_json":"https://pith.science/api/pith-number/VVNM2PMZGPKE6OBEK7HIOZI75C/events.json","paper":"https://pith.science/paper/VVNM2PMZ"},"agent_actions":{"view_html":"https://pith.science/pith/VVNM2PMZGPKE6OBEK7HIOZI75C","download_json":"https://pith.science/pith/VVNM2PMZGPKE6OBEK7HIOZI75C.json","view_paper":"https://pith.science/paper/VVNM2PMZ","resolve_alias":"https://pith.science/api/pith-number/resolve?arxiv=2607.24503&json=true","fetch_graph":"https://pith.science/api/pith-number/VVNM2PMZGPKE6OBEK7HIOZI75C/graph.json","fetch_events":"https://pith.science/api/pith-number/VVNM2PMZGPKE6OBEK7HIOZI75C/events.json","actions":{"anchor_timestamp":"https://pith.science/pith/VVNM2PMZGPKE6OBEK7HIOZI75C/action/timestamp_anchor","attest_storage":"https://pith.science/pith/VVNM2PMZGPKE6OBEK7HIOZI75C/action/storage_attestation","attest_author":"https://pith.science/pith/VVNM2PMZGPKE6OBEK7HIOZI75C/action/author_attestation","sign_citation":"https://pith.science/pith/VVNM2PMZGPKE6OBEK7HIOZI75C/action/citation_signature","submit_replication":"https://pith.science/pith/VVNM2PMZGPKE6OBEK7HIOZI75C/action/replication_record"}},"created_at":"2026-07-28T02:24:06.925261+00:00","updated_at":"2026-07-28T02:24:06.925261+00:00"}