{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2019:W35AQSHHK6YMRGZZPFHCQ7ZND6","short_pith_number":"pith:W35AQSHH","canonical_record":{"source":{"id":"1908.10240","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.med-ph","submitted_at":"2019-08-22T03:26:39Z","cross_cats_sorted":["q-bio.NC"],"title_canon_sha256":"4baa1094edbdf0cf9af1b9942c43736f9568299b4b9b56d60e6db3b0608bea8b","abstract_canon_sha256":"74bd728887d68ae473471aa5253008957509dccd91fd1921750e889081fcdc29"},"schema_version":"1.0"},"canonical_sha256":"b6fa0848e757b0c89b39794e287f2d1fa62458f8779d212b86a6b5be4394d725","source":{"kind":"arxiv","id":"1908.10240","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1908.10240","created_at":"2026-07-05T00:00:10Z"},{"alias_kind":"arxiv_version","alias_value":"1908.10240v1","created_at":"2026-07-05T00:00:10Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1908.10240","created_at":"2026-07-05T00:00:10Z"},{"alias_kind":"pith_short_12","alias_value":"W35AQSHHK6YM","created_at":"2026-07-05T00:00:10Z"},{"alias_kind":"pith_short_16","alias_value":"W35AQSHHK6YMRGZZ","created_at":"2026-07-05T00:00:10Z"},{"alias_kind":"pith_short_8","alias_value":"W35AQSHH","created_at":"2026-07-05T00:00:10Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2019:W35AQSHHK6YMRGZZPFHCQ7ZND6","target":"record","payload":{"canonical_record":{"source":{"id":"1908.10240","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.med-ph","submitted_at":"2019-08-22T03:26:39Z","cross_cats_sorted":["q-bio.NC"],"title_canon_sha256":"4baa1094edbdf0cf9af1b9942c43736f9568299b4b9b56d60e6db3b0608bea8b","abstract_canon_sha256":"74bd728887d68ae473471aa5253008957509dccd91fd1921750e889081fcdc29"},"schema_version":"1.0"},"canonical_sha256":"b6fa0848e757b0c89b39794e287f2d1fa62458f8779d212b86a6b5be4394d725","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T00:00:10.557560Z","signature_b64":"nc9RFx5WbA8I50s0SbwP0Wb0WvXyuLrDgnjP1W0ImVdR1c7Eoo5K1popgrs8GUWhkX2cQpKkLep3hmwvTG+kDg==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"b6fa0848e757b0c89b39794e287f2d1fa62458f8779d212b86a6b5be4394d725","last_reissued_at":"2026-07-05T00:00:10.557141Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T00:00:10.557141Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1908.10240","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T00:00:10Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"TpK/dKtB5k0LS3fXs3YvIfAAGiHcbdIjTPxQMK0ZxhCP8ARyd/DuAWCIYzPoMjDW+TB+KUvBJV/E//SGd2qsDg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-23T06:06:57.617984Z"},"content_sha256":"d079eee4d70b8d7c761ead285a78cf94b62e259aad401727eb4c69d2dfc8a78c","schema_version":"1.0","event_id":"sha256:d079eee4d70b8d7c761ead285a78cf94b62e259aad401727eb4c69d2dfc8a78c"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2019:W35AQSHHK6YMRGZZPFHCQ7ZND6","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Pain Analysis, in Premature Infants, Using Near Infrared Spectroscopy (NIRS)","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["q-bio.NC"],"primary_cat":"physics.med-ph","authors_text":"Ghada Zamzmi, Judy Zarit, Marcia Kneusel, Maria Gieron, Matthew Compton, Rahul Mhaskar, Terri Ashmeade","submitted_at":"2019-08-22T03:26:39Z","abstract_excerpt":"Background: The role of neonatal pain on the developing nervous system is not completely understood, but evidence suggests that sensory pathways are influenced by an infants pain experience. Research has shown that an infants previous pain experiences lead to an increased, and likely abnormal, response to subsequent painful stimuli. We are working to improve neonatal pain detection through automated devices that continuously monitor an infant. The current study outlines some of the initial steps we have taken to evaluate Near Infrared Spectroscopy (NIRS) as a technology to detect neonatal pain"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1908.10240","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/1908.10240/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T00:00:10Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"NdsNoGDd/9Y7brM4XI0NXuXjt7hXD4L1fgXxVTBkzz1N1MSD8ha46+YmBY8+0Hi91bLqCsbQ9iGmg4tfawRQAw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-23T06:06:57.618394Z"},"content_sha256":"22bec78c71496605dcfae45963591b685e3998ede3df9aae93f467753af1577d","schema_version":"1.0","event_id":"sha256:22bec78c71496605dcfae45963591b685e3998ede3df9aae93f467753af1577d"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/W35AQSHHK6YMRGZZPFHCQ7ZND6/bundle.json","state_url":"https://pith.science/pith/W35AQSHHK6YMRGZZPFHCQ7ZND6/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/W35AQSHHK6YMRGZZPFHCQ7ZND6/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-08-23T06:06:57Z","links":{"resolver":"https://pith.science/pith/W35AQSHHK6YMRGZZPFHCQ7ZND6","bundle":"https://pith.science/pith/W35AQSHHK6YMRGZZPFHCQ7ZND6/bundle.json","state":"https://pith.science/pith/W35AQSHHK6YMRGZZPFHCQ7ZND6/state.json","well_known_bundle":"https://pith.science/.well-known/pith/W35AQSHHK6YMRGZZPFHCQ7ZND6/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2019:W35AQSHHK6YMRGZZPFHCQ7ZND6","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"74bd728887d68ae473471aa5253008957509dccd91fd1921750e889081fcdc29","cross_cats_sorted":["q-bio.NC"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.med-ph","submitted_at":"2019-08-22T03:26:39Z","title_canon_sha256":"4baa1094edbdf0cf9af1b9942c43736f9568299b4b9b56d60e6db3b0608bea8b"},"schema_version":"1.0","source":{"id":"1908.10240","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1908.10240","created_at":"2026-07-05T00:00:10Z"},{"alias_kind":"arxiv_version","alias_value":"1908.10240v1","created_at":"2026-07-05T00:00:10Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1908.10240","created_at":"2026-07-05T00:00:10Z"},{"alias_kind":"pith_short_12","alias_value":"W35AQSHHK6YM","created_at":"2026-07-05T00:00:10Z"},{"alias_kind":"pith_short_16","alias_value":"W35AQSHHK6YMRGZZ","created_at":"2026-07-05T00:00:10Z"},{"alias_kind":"pith_short_8","alias_value":"W35AQSHH","created_at":"2026-07-05T00:00:10Z"}],"graph_snapshots":[{"event_id":"sha256:22bec78c71496605dcfae45963591b685e3998ede3df9aae93f467753af1577d","target":"graph","created_at":"2026-07-05T00:00:10Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/1908.10240/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Background: The role of neonatal pain on the developing nervous system is not completely understood, but evidence suggests that sensory pathways are influenced by an infants pain experience. Research has shown that an infants previous pain experiences lead to an increased, and likely abnormal, response to subsequent painful stimuli. We are working to improve neonatal pain detection through automated devices that continuously monitor an infant. The current study outlines some of the initial steps we have taken to evaluate Near Infrared Spectroscopy (NIRS) as a technology to detect neonatal pain","authors_text":"Ghada Zamzmi, Judy Zarit, Marcia Kneusel, Maria Gieron, Matthew Compton, Rahul Mhaskar, Terri Ashmeade","cross_cats":["q-bio.NC"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.med-ph","submitted_at":"2019-08-22T03:26:39Z","title":"Pain Analysis, in Premature Infants, Using Near Infrared Spectroscopy (NIRS)"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1908.10240","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:d079eee4d70b8d7c761ead285a78cf94b62e259aad401727eb4c69d2dfc8a78c","target":"record","created_at":"2026-07-05T00:00:10Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"74bd728887d68ae473471aa5253008957509dccd91fd1921750e889081fcdc29","cross_cats_sorted":["q-bio.NC"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.med-ph","submitted_at":"2019-08-22T03:26:39Z","title_canon_sha256":"4baa1094edbdf0cf9af1b9942c43736f9568299b4b9b56d60e6db3b0608bea8b"},"schema_version":"1.0","source":{"id":"1908.10240","kind":"arxiv","version":1}},"canonical_sha256":"b6fa0848e757b0c89b39794e287f2d1fa62458f8779d212b86a6b5be4394d725","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"b6fa0848e757b0c89b39794e287f2d1fa62458f8779d212b86a6b5be4394d725","first_computed_at":"2026-07-05T00:00:10.557141Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T00:00:10.557141Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"nc9RFx5WbA8I50s0SbwP0Wb0WvXyuLrDgnjP1W0ImVdR1c7Eoo5K1popgrs8GUWhkX2cQpKkLep3hmwvTG+kDg==","signature_status":"signed_v1","signed_at":"2026-07-05T00:00:10.557560Z","signed_message":"canonical_sha256_bytes"},"source_id":"1908.10240","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:d079eee4d70b8d7c761ead285a78cf94b62e259aad401727eb4c69d2dfc8a78c","sha256:22bec78c71496605dcfae45963591b685e3998ede3df9aae93f467753af1577d"],"state_sha256":"ef963ed5ccac28e8e1c4e786e545a4f4e82122d503f35581c2d698e2e42f4c4d"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"rVqunmEXMgCVGOtHk/Fn+2E0yFZzMl0aOmJldANw9x+30qf2lE3Pizdjw5nuJJYxGHpSU9S0h9Tv/Ed/D91rAg==","signed_message":"bundle_sha256_bytes","signed_at":"2026-08-23T06:06:57.620862Z","bundle_sha256":"ed78e64a21576ef170ad16134b5f4b87a46f00d31bed34185416939cc5bf446f"}}