{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2022:WGKVCDXTVJPB7LA36BJDZJR553","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"d78e63ff8bb0b3904ac1a42b3a0a7b0ba8df4113286d0a56340873f62fafa29f","cross_cats_sorted":["cs.CV"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"eess.IV","submitted_at":"2022-03-12T12:40:20Z","title_canon_sha256":"aec7c13851a7d600f6192b303ec071b015ebdf2c3138c62838cb5756d259984c"},"schema_version":"1.0","source":{"id":"2203.06425","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2203.06425","created_at":"2026-07-05T04:13:13Z"},{"alias_kind":"arxiv_version","alias_value":"2203.06425v1","created_at":"2026-07-05T04:13:13Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2203.06425","created_at":"2026-07-05T04:13:13Z"},{"alias_kind":"pith_short_12","alias_value":"WGKVCDXTVJPB","created_at":"2026-07-05T04:13:13Z"},{"alias_kind":"pith_short_16","alias_value":"WGKVCDXTVJPB7LA3","created_at":"2026-07-05T04:13:13Z"},{"alias_kind":"pith_short_8","alias_value":"WGKVCDXT","created_at":"2026-07-05T04:13:13Z"}],"graph_snapshots":[{"event_id":"sha256:48f335182f49a4e67ef6ba7e74dd0ed9343eeec5a6f0d1ad490157d749c6980f","target":"graph","created_at":"2026-07-05T04:13:13Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2203.06425/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Estimating clinically-relevant vascular features following vessel segmentation is a standard pipeline for retinal vessel analysis, which provides potential ocular biomarkers for both ophthalmic disease and systemic disease. In this work, we integrate these clinical features into a novel vascular feature optimised loss function (VAFO-Loss), in order to regularise networks to produce segmentation maps, with which more accurate vascular features can be derived. Two common vascular features, vessel density and fractal dimension, are identified to be sensitive to intra-segment misclassification, wh","authors_text":"An Zhao, Daniel C. Alexander, Moucheng Xu, Pearse A. Keane, Siegfried K. Wagner, Stefano B. Blumberg, Yipeng Hu, Yukun Zhou","cross_cats":["cs.CV"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"eess.IV","submitted_at":"2022-03-12T12:40:20Z","title":"VAFO-Loss: VAscular Feature Optimised Loss Function for Retinal Artery/Vein Segmentation"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2203.06425","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:730c20346a49ab792c251e69f3b4ed0f0ab694fd9a2629fdba81be447275d57c","target":"record","created_at":"2026-07-05T04:13:13Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"d78e63ff8bb0b3904ac1a42b3a0a7b0ba8df4113286d0a56340873f62fafa29f","cross_cats_sorted":["cs.CV"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"eess.IV","submitted_at":"2022-03-12T12:40:20Z","title_canon_sha256":"aec7c13851a7d600f6192b303ec071b015ebdf2c3138c62838cb5756d259984c"},"schema_version":"1.0","source":{"id":"2203.06425","kind":"arxiv","version":1}},"canonical_sha256":"b195510ef3aa5e1fac1bf0523ca63deece00754b5a773a86b6287134089aa50a","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"b195510ef3aa5e1fac1bf0523ca63deece00754b5a773a86b6287134089aa50a","first_computed_at":"2026-07-05T04:13:13.150527Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T04:13:13.150527Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"tpa2FXyCSMUMaT/HEczx9vMwSEXsy6PKp3JbYf8AOLK60/ohaAu2O0hGP0NL07MaSvvzdJ1D81xBzs9EuldHBw==","signature_status":"signed_v1","signed_at":"2026-07-05T04:13:13.150927Z","signed_message":"canonical_sha256_bytes"},"source_id":"2203.06425","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:730c20346a49ab792c251e69f3b4ed0f0ab694fd9a2629fdba81be447275d57c","sha256:48f335182f49a4e67ef6ba7e74dd0ed9343eeec5a6f0d1ad490157d749c6980f"],"state_sha256":"9ef8b71eb9fbdab4b2de00d8a4d36b057ea00d675ebc1fed01afe86c734912ae"}