{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2020:WXM7EKWU4F2DIP5BG5IIRMOJYJ","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"d5078327948bafd6429a5507af026f8c855fd063b74c1d0c76fb290493927b10","cross_cats_sorted":["cs.CV","cs.LG","physics.optics"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"eess.IV","submitted_at":"2020-03-24T18:42:23Z","title_canon_sha256":"0545fc7cad943b44d85a0446ecad633aab503201b9560190d28dfc75b2ad9aa6"},"schema_version":"1.0","source":{"id":"2003.11064","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2003.11064","created_at":"2026-07-05T00:50:30Z"},{"alias_kind":"arxiv_version","alias_value":"2003.11064v1","created_at":"2026-07-05T00:50:30Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2003.11064","created_at":"2026-07-05T00:50:30Z"},{"alias_kind":"pith_short_12","alias_value":"WXM7EKWU4F2D","created_at":"2026-07-05T00:50:30Z"},{"alias_kind":"pith_short_16","alias_value":"WXM7EKWU4F2DIP5B","created_at":"2026-07-05T00:50:30Z"},{"alias_kind":"pith_short_8","alias_value":"WXM7EKWU","created_at":"2026-07-05T00:50:30Z"}],"graph_snapshots":[{"event_id":"sha256:baf8c6f84ff8fcc6e00c7c5cb20c8235b464610a07950291993aba85d853fd42","target":"graph","created_at":"2026-07-05T00:50:30Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2003.11064/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Structured illumination microscopy (SIM) has become an important technique for optical super-resolution imaging because it allows a doubling of image resolution at speeds compatible for live-cell imaging. However, the reconstruction of SIM images is often slow and prone to artefacts. Here we propose a versatile reconstruction method, ML-SIM, which makes use of machine learning. The model is an end-to-end deep residual neural network that is trained on a simulated data set to be free of common SIM artefacts. ML-SIM is thus robust to noise and irregularities in the illumination patterns of the r","authors_text":"Charles N. Christensen, Clemens F. Kaminski, Edward N. Ward, Pietro Lio","cross_cats":["cs.CV","cs.LG","physics.optics"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"eess.IV","submitted_at":"2020-03-24T18:42:23Z","title":"ML-SIM: A deep neural network for reconstruction of structured illumination microscopy images"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2003.11064","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:dee24717f4a383ed714d0de1465255d2def27b7be7cc2129f6c1b4f394877f93","target":"record","created_at":"2026-07-05T00:50:30Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"d5078327948bafd6429a5507af026f8c855fd063b74c1d0c76fb290493927b10","cross_cats_sorted":["cs.CV","cs.LG","physics.optics"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"eess.IV","submitted_at":"2020-03-24T18:42:23Z","title_canon_sha256":"0545fc7cad943b44d85a0446ecad633aab503201b9560190d28dfc75b2ad9aa6"},"schema_version":"1.0","source":{"id":"2003.11064","kind":"arxiv","version":1}},"canonical_sha256":"b5d9f22ad4e174343fa1375088b1c9c26f8afa1f5de9cd473cca6b3834243174","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"b5d9f22ad4e174343fa1375088b1c9c26f8afa1f5de9cd473cca6b3834243174","first_computed_at":"2026-07-05T00:50:30.578043Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T00:50:30.578043Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"1bEE0wlp8SJJcLlZArAXay5tVKcHexKXhLR+bkUgWKNgoW1bdnTLo5U0NeFRX2sLZKRhW5Xh0PJW+7UZFLy7AA==","signature_status":"signed_v1","signed_at":"2026-07-05T00:50:30.578467Z","signed_message":"canonical_sha256_bytes"},"source_id":"2003.11064","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:dee24717f4a383ed714d0de1465255d2def27b7be7cc2129f6c1b4f394877f93","sha256:baf8c6f84ff8fcc6e00c7c5cb20c8235b464610a07950291993aba85d853fd42"],"state_sha256":"a6f22dc6290ac0272309485465c3952db42f262affd548d611ea8e500b2a79f4"}