{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2017:WYWILQQULXDXKXM4BJA6KOZKNK","short_pith_number":"pith:WYWILQQU","canonical_record":{"source":{"id":"1707.07852","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2017-07-25T08:55:26Z","cross_cats_sorted":[],"title_canon_sha256":"4b7d29c157137774ace735154aa953fca8dbf2401820be221acc58589c9d953a","abstract_canon_sha256":"cd7531fccae8e0092cea29fa923fcf1a754ff4a21642881c5d628fe91b3b61b6"},"schema_version":"1.0"},"canonical_sha256":"b62c85c2145dc7755d9c0a41e53b2a6a97d74041d3c6aa5cc6ef050cb0e09b3f","source":{"kind":"arxiv","id":"1707.07852","version":2},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1707.07852","created_at":"2026-05-18T00:38:41Z"},{"alias_kind":"arxiv_version","alias_value":"1707.07852v2","created_at":"2026-05-18T00:38:41Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1707.07852","created_at":"2026-05-18T00:38:41Z"},{"alias_kind":"pith_short_12","alias_value":"WYWILQQULXDX","created_at":"2026-05-18T12:31:53Z"},{"alias_kind":"pith_short_16","alias_value":"WYWILQQULXDXKXM4","created_at":"2026-05-18T12:31:53Z"},{"alias_kind":"pith_short_8","alias_value":"WYWILQQU","created_at":"2026-05-18T12:31:53Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2017:WYWILQQULXDXKXM4BJA6KOZKNK","target":"record","payload":{"canonical_record":{"source":{"id":"1707.07852","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2017-07-25T08:55:26Z","cross_cats_sorted":[],"title_canon_sha256":"4b7d29c157137774ace735154aa953fca8dbf2401820be221acc58589c9d953a","abstract_canon_sha256":"cd7531fccae8e0092cea29fa923fcf1a754ff4a21642881c5d628fe91b3b61b6"},"schema_version":"1.0"},"canonical_sha256":"b62c85c2145dc7755d9c0a41e53b2a6a97d74041d3c6aa5cc6ef050cb0e09b3f","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T00:38:41.428725Z","signature_b64":"0NVPVa2OigKKf7gm/t066oxD0hXTVTkrxsS0S7wyVIk4l2qdaa7q6lZfY4qxUi3Vp/HrCJmjs1AovOZ8n32AAg==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"b62c85c2145dc7755d9c0a41e53b2a6a97d74041d3c6aa5cc6ef050cb0e09b3f","last_reissued_at":"2026-05-18T00:38:41.428162Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T00:38:41.428162Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1707.07852","source_version":2,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T00:38:41Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"n3pov37hFvfWC2HQKYU8a7n/wZcuO31Noychp4XNvfgbxCTj0aBdhQsbx5VfNiFCBu34zxzNM+xvJFMmNU67AQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-08T05:17:40.994573Z"},"content_sha256":"72ad6b9044ec5f2ca952300535f983622e31a53903af40cf62ea252a34dcfd88","schema_version":"1.0","event_id":"sha256:72ad6b9044ec5f2ca952300535f983622e31a53903af40cf62ea252a34dcfd88"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2017:WYWILQQULXDXKXM4BJA6KOZKNK","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"A Computational Resolution of the Inverse Problem of Kinetic Capillary Electrophoresis (KCE)","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.QM","authors_text":"J\\'ozsef Vass, Sergey N. Krylov","submitted_at":"2017-07-25T08:55:26Z","abstract_excerpt":"Determining kinetic rate constants is a highly relevant problem in biochemistry, so various methods have been designed to extract them from experimental data. Such methods have two main components: the experimental apparatus and the subsequent analysis, the latter often dependent on mathematical theory. Thus the theoretical approach taken influences the effectiveness of constant determination. A computational inverse problem approach is hereby presented, which does not merely give a single rough approximation of the sought constants, but is inherently capable of determining them from exact sig"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1707.07852","kind":"arxiv","version":2},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T00:38:41Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"z1U8mDUUn5n/EwRFSAjKfsxZh0KbjbvjotSpTiDvdGVgpG8E/KDagRt+ZeUrO5b0zmfe3qycZ75UTAjsekyrBQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-08T05:17:40.995296Z"},"content_sha256":"ea5c793edf54cdd9cee004754d2e860a6003482c553e9d20f8b2fc93fd06517a","schema_version":"1.0","event_id":"sha256:ea5c793edf54cdd9cee004754d2e860a6003482c553e9d20f8b2fc93fd06517a"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/WYWILQQULXDXKXM4BJA6KOZKNK/bundle.json","state_url":"https://pith.science/pith/WYWILQQULXDXKXM4BJA6KOZKNK/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/WYWILQQULXDXKXM4BJA6KOZKNK/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-08T05:17:40Z","links":{"resolver":"https://pith.science/pith/WYWILQQULXDXKXM4BJA6KOZKNK","bundle":"https://pith.science/pith/WYWILQQULXDXKXM4BJA6KOZKNK/bundle.json","state":"https://pith.science/pith/WYWILQQULXDXKXM4BJA6KOZKNK/state.json","well_known_bundle":"https://pith.science/.well-known/pith/WYWILQQULXDXKXM4BJA6KOZKNK/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2017:WYWILQQULXDXKXM4BJA6KOZKNK","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"cd7531fccae8e0092cea29fa923fcf1a754ff4a21642881c5d628fe91b3b61b6","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2017-07-25T08:55:26Z","title_canon_sha256":"4b7d29c157137774ace735154aa953fca8dbf2401820be221acc58589c9d953a"},"schema_version":"1.0","source":{"id":"1707.07852","kind":"arxiv","version":2}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1707.07852","created_at":"2026-05-18T00:38:41Z"},{"alias_kind":"arxiv_version","alias_value":"1707.07852v2","created_at":"2026-05-18T00:38:41Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1707.07852","created_at":"2026-05-18T00:38:41Z"},{"alias_kind":"pith_short_12","alias_value":"WYWILQQULXDX","created_at":"2026-05-18T12:31:53Z"},{"alias_kind":"pith_short_16","alias_value":"WYWILQQULXDXKXM4","created_at":"2026-05-18T12:31:53Z"},{"alias_kind":"pith_short_8","alias_value":"WYWILQQU","created_at":"2026-05-18T12:31:53Z"}],"graph_snapshots":[{"event_id":"sha256:ea5c793edf54cdd9cee004754d2e860a6003482c553e9d20f8b2fc93fd06517a","target":"graph","created_at":"2026-05-18T00:38:41Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Determining kinetic rate constants is a highly relevant problem in biochemistry, so various methods have been designed to extract them from experimental data. Such methods have two main components: the experimental apparatus and the subsequent analysis, the latter often dependent on mathematical theory. Thus the theoretical approach taken influences the effectiveness of constant determination. A computational inverse problem approach is hereby presented, which does not merely give a single rough approximation of the sought constants, but is inherently capable of determining them from exact sig","authors_text":"J\\'ozsef Vass, Sergey N. Krylov","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2017-07-25T08:55:26Z","title":"A Computational Resolution of the Inverse Problem of Kinetic Capillary Electrophoresis (KCE)"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1707.07852","kind":"arxiv","version":2},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:72ad6b9044ec5f2ca952300535f983622e31a53903af40cf62ea252a34dcfd88","target":"record","created_at":"2026-05-18T00:38:41Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"cd7531fccae8e0092cea29fa923fcf1a754ff4a21642881c5d628fe91b3b61b6","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.QM","submitted_at":"2017-07-25T08:55:26Z","title_canon_sha256":"4b7d29c157137774ace735154aa953fca8dbf2401820be221acc58589c9d953a"},"schema_version":"1.0","source":{"id":"1707.07852","kind":"arxiv","version":2}},"canonical_sha256":"b62c85c2145dc7755d9c0a41e53b2a6a97d74041d3c6aa5cc6ef050cb0e09b3f","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"b62c85c2145dc7755d9c0a41e53b2a6a97d74041d3c6aa5cc6ef050cb0e09b3f","first_computed_at":"2026-05-18T00:38:41.428162Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T00:38:41.428162Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"0NVPVa2OigKKf7gm/t066oxD0hXTVTkrxsS0S7wyVIk4l2qdaa7q6lZfY4qxUi3Vp/HrCJmjs1AovOZ8n32AAg==","signature_status":"signed_v1","signed_at":"2026-05-18T00:38:41.428725Z","signed_message":"canonical_sha256_bytes"},"source_id":"1707.07852","source_kind":"arxiv","source_version":2}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:72ad6b9044ec5f2ca952300535f983622e31a53903af40cf62ea252a34dcfd88","sha256:ea5c793edf54cdd9cee004754d2e860a6003482c553e9d20f8b2fc93fd06517a"],"state_sha256":"250e2a743fd9d8b0bc51e1959872b6b31d800c2f2fd26d5cacbe1ac528629b5c"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"TzlWRTVv2xzxBpl1vfEPpteAPokZc3smNATMGpHES8JXRZsttUufo1AXe6q8Xw/75kTBAQOcHTfMANJFiGK8BQ==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-08T05:17:40.999188Z","bundle_sha256":"eaeb7bee81c50ce0cb23728744a69d03eb80c9b7eff5f5006254cfe7c3ef886b"}}