{"record_type":"pith_number_record","schema_url":"https://pith.science/schemas/pith-number/v1.json","pith_number":"pith:2012:XH22DMYXRIEPEZM3N4EIYGXSMJ","short_pith_number":"pith:XH22DMYX","schema_version":"1.0","canonical_sha256":"b9f5a1b3178a08f2659b6f088c1af262726539fb9f21ce1425900424cbec9739","source":{"kind":"arxiv","id":"1209.6210","version":1},"attestation_state":"computed","paper":{"title":"Correlation analysis of enzymatic reaction of a single protein molecule","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["q-bio.QM"],"primary_cat":"stat.AP","authors_text":"Chao Du, S. C. Kou","submitted_at":"2012-09-27T12:47:11Z","abstract_excerpt":"New advances in nano sciences open the door for scientists to study biological processes on a microscopic molecule-by-molecule basis. Recent single-molecule biophysical experiments on enzyme systems, in particular, reveal that enzyme molecules behave fundamentally differently from what classical model predicts. A stochastic network model was previously proposed to explain the experimental discovery. This paper conducts detailed theoretical and data analyses of the stochastic network model, focusing on the correlation structure of the successive reaction times of a single enzyme molecule. We in"},"verification_status":{"content_addressed":true,"pith_receipt":true,"author_attested":false,"weak_author_claims":0,"strong_author_claims":0,"externally_anchored":false,"storage_verified":false,"citation_signatures":0,"replication_records":0,"graph_snapshot":true,"references_resolved":false,"formal_links_present":false},"canonical_record":{"source":{"id":"1209.6210","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"stat.AP","submitted_at":"2012-09-27T12:47:11Z","cross_cats_sorted":["q-bio.QM"],"title_canon_sha256":"1ef321f46dec68289f34417ef18c888fb84747efe21a15d2cb5a10b04fa18026","abstract_canon_sha256":"5bedc21f21f6cce85544258e7816179d97494945a86982794278133f389ea197"},"schema_version":"1.0"},"receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T03:44:35.014107Z","signature_b64":"3w1KV36r3oTjzdI4DXH5oaEHrhJgcKinKg6C/sdQnUe2KTzvcv/izfTxJjLJPf/9e5B7zjPV91u+Q/e8pAR+AQ==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"b9f5a1b3178a08f2659b6f088c1af262726539fb9f21ce1425900424cbec9739","last_reissued_at":"2026-05-18T03:44:35.013499Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T03:44:35.013499Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"graph_snapshot":{"paper":{"title":"Correlation analysis of enzymatic reaction of a single protein molecule","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["q-bio.QM"],"primary_cat":"stat.AP","authors_text":"Chao Du, S. C. Kou","submitted_at":"2012-09-27T12:47:11Z","abstract_excerpt":"New advances in nano sciences open the door for scientists to study biological processes on a microscopic molecule-by-molecule basis. Recent single-molecule biophysical experiments on enzyme systems, in particular, reveal that enzyme molecules behave fundamentally differently from what classical model predicts. A stochastic network model was previously proposed to explain the experimental discovery. This paper conducts detailed theoretical and data analyses of the stochastic network model, focusing on the correlation structure of the successive reaction times of a single enzyme molecule. We in"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1209.6210","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"aliases":[{"alias_kind":"arxiv","alias_value":"1209.6210","created_at":"2026-05-18T03:44:35.013606+00:00"},{"alias_kind":"arxiv_version","alias_value":"1209.6210v1","created_at":"2026-05-18T03:44:35.013606+00:00"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1209.6210","created_at":"2026-05-18T03:44:35.013606+00:00"},{"alias_kind":"pith_short_12","alias_value":"XH22DMYXRIEP","created_at":"2026-05-18T12:27:27.928770+00:00"},{"alias_kind":"pith_short_16","alias_value":"XH22DMYXRIEPEZM3","created_at":"2026-05-18T12:27:27.928770+00:00"},{"alias_kind":"pith_short_8","alias_value":"XH22DMYX","created_at":"2026-05-18T12:27:27.928770+00:00"}],"events":[],"event_summary":{},"paper_claims":[],"inbound_citations":{"count":0,"internal_anchor_count":0,"sample":[]},"formal_canon":{"evidence_count":0,"sample":[],"anchors":[]},"links":{"html":"https://pith.science/pith/XH22DMYXRIEPEZM3N4EIYGXSMJ","json":"https://pith.science/pith/XH22DMYXRIEPEZM3N4EIYGXSMJ.json","graph_json":"https://pith.science/api/pith-number/XH22DMYXRIEPEZM3N4EIYGXSMJ/graph.json","events_json":"https://pith.science/api/pith-number/XH22DMYXRIEPEZM3N4EIYGXSMJ/events.json","paper":"https://pith.science/paper/XH22DMYX"},"agent_actions":{"view_html":"https://pith.science/pith/XH22DMYXRIEPEZM3N4EIYGXSMJ","download_json":"https://pith.science/pith/XH22DMYXRIEPEZM3N4EIYGXSMJ.json","view_paper":"https://pith.science/paper/XH22DMYX","resolve_alias":"https://pith.science/api/pith-number/resolve?arxiv=1209.6210&json=true","fetch_graph":"https://pith.science/api/pith-number/XH22DMYXRIEPEZM3N4EIYGXSMJ/graph.json","fetch_events":"https://pith.science/api/pith-number/XH22DMYXRIEPEZM3N4EIYGXSMJ/events.json","actions":{"anchor_timestamp":"https://pith.science/pith/XH22DMYXRIEPEZM3N4EIYGXSMJ/action/timestamp_anchor","attest_storage":"https://pith.science/pith/XH22DMYXRIEPEZM3N4EIYGXSMJ/action/storage_attestation","attest_author":"https://pith.science/pith/XH22DMYXRIEPEZM3N4EIYGXSMJ/action/author_attestation","sign_citation":"https://pith.science/pith/XH22DMYXRIEPEZM3N4EIYGXSMJ/action/citation_signature","submit_replication":"https://pith.science/pith/XH22DMYXRIEPEZM3N4EIYGXSMJ/action/replication_record"}},"created_at":"2026-05-18T03:44:35.013606+00:00","updated_at":"2026-05-18T03:44:35.013606+00:00"}