{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2019:XIHTCL2M2FQXFZLWIY37MORSWO","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"ed9e02d655b1e627223b0f5e567fa3a26b947f1ec83dd598c52c399c9d9ab729","cross_cats_sorted":["physics.optics"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2019-01-21T22:58:34Z","title_canon_sha256":"4da2a1039f6c3339e8d9bfe9a7f818e761c690910401c5ff3c1e857ca2653e6c"},"schema_version":"1.0","source":{"id":"1901.08104","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1901.08104","created_at":"2026-05-17T23:55:37Z"},{"alias_kind":"arxiv_version","alias_value":"1901.08104v1","created_at":"2026-05-17T23:55:37Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1901.08104","created_at":"2026-05-17T23:55:37Z"},{"alias_kind":"pith_short_12","alias_value":"XIHTCL2M2FQX","created_at":"2026-05-18T12:33:33Z"},{"alias_kind":"pith_short_16","alias_value":"XIHTCL2M2FQXFZLW","created_at":"2026-05-18T12:33:33Z"},{"alias_kind":"pith_short_8","alias_value":"XIHTCL2M","created_at":"2026-05-18T12:33:33Z"}],"graph_snapshots":[{"event_id":"sha256:efba7646782c7f7f06b307090e2ef8efe741c548bf71ba95461ad2642a90d6c2","target":"graph","created_at":"2026-05-17T23:55:37Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Non-degradable fluorophores that accumulate as Lipofuscin in retinal pigment epithelium (RPE) cells has been a major source of intrinsic biomarker for quantifying the progression of several diseases, including age-related macular degeneration, Stargardt disease and, more. Recent progression in quantifying these diseases is entertained mostly by a few noninvasive imaging techniques, relied either on the life-time of the retinoid-fluorophores or, their linear and, non-linear absorption cross-sections. Apart from these intrinsic properties, a native, excited state dipole-dipole interaction mediat","authors_text":"Pengfei Zhang, Ratheesh K. Meleppat, Suman K. Manna","cross_cats":["physics.optics"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2019-01-21T22:58:34Z","title":"Built-in Fluorescence Anisotropy: an in vivo Imaging Probe for bis-Retinoid Products in Retina"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1901.08104","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:fc646af04e39ff69ccafb277e6ee079e99d6c50a32baf11491a7decba9ef65a2","target":"record","created_at":"2026-05-17T23:55:37Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"ed9e02d655b1e627223b0f5e567fa3a26b947f1ec83dd598c52c399c9d9ab729","cross_cats_sorted":["physics.optics"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2019-01-21T22:58:34Z","title_canon_sha256":"4da2a1039f6c3339e8d9bfe9a7f818e761c690910401c5ff3c1e857ca2653e6c"},"schema_version":"1.0","source":{"id":"1901.08104","kind":"arxiv","version":1}},"canonical_sha256":"ba0f312f4cd16172e5764637f63a32b3b1fa2efd7cbaec6cd2b9b984367c1804","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"ba0f312f4cd16172e5764637f63a32b3b1fa2efd7cbaec6cd2b9b984367c1804","first_computed_at":"2026-05-17T23:55:37.896356Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-17T23:55:37.896356Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"ojsaohzV/pdmPNxhbbj89ZhmR9YaEbyIu7D9/uV5je8Cg83Ano9PCUSMKm93MyfFzkPy3QeFbW7X6Yuw9zofCg==","signature_status":"signed_v1","signed_at":"2026-05-17T23:55:37.896793Z","signed_message":"canonical_sha256_bytes"},"source_id":"1901.08104","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:fc646af04e39ff69ccafb277e6ee079e99d6c50a32baf11491a7decba9ef65a2","sha256:efba7646782c7f7f06b307090e2ef8efe741c548bf71ba95461ad2642a90d6c2"],"state_sha256":"d6667e6a0ca84898b7620a4b9461a852a1900438766b080fa35198fcb42996d9"}