{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2013:XIWGOU64UVAA2ZXLRA6A6OLXUV","short_pith_number":"pith:XIWGOU64","canonical_record":{"source":{"id":"1312.5537","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.MN","submitted_at":"2013-12-19T13:24:43Z","cross_cats_sorted":["cond-mat.dis-nn","cond-mat.stat-mech","q-bio.GN","q-bio.QM"],"title_canon_sha256":"5f62e431e0946ed034ff199281e004045001b5c8392a4203b9fdd11c7f0f6fdc","abstract_canon_sha256":"2a9724c9fb64e4ad19b0b1973dd923a317d0702eae0a8991d315f4b329ac1fda"},"schema_version":"1.0"},"canonical_sha256":"ba2c6753dca5400d66eb883c0f3977a552912d3b1b55d8d64500ce94190ac2c7","source":{"kind":"arxiv","id":"1312.5537","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1312.5537","created_at":"2026-05-18T01:45:43Z"},{"alias_kind":"arxiv_version","alias_value":"1312.5537v1","created_at":"2026-05-18T01:45:43Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1312.5537","created_at":"2026-05-18T01:45:43Z"},{"alias_kind":"pith_short_12","alias_value":"XIWGOU64UVAA","created_at":"2026-05-18T12:28:06Z"},{"alias_kind":"pith_short_16","alias_value":"XIWGOU64UVAA2ZXL","created_at":"2026-05-18T12:28:06Z"},{"alias_kind":"pith_short_8","alias_value":"XIWGOU64","created_at":"2026-05-18T12:28:06Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2013:XIWGOU64UVAA2ZXLRA6A6OLXUV","target":"record","payload":{"canonical_record":{"source":{"id":"1312.5537","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.MN","submitted_at":"2013-12-19T13:24:43Z","cross_cats_sorted":["cond-mat.dis-nn","cond-mat.stat-mech","q-bio.GN","q-bio.QM"],"title_canon_sha256":"5f62e431e0946ed034ff199281e004045001b5c8392a4203b9fdd11c7f0f6fdc","abstract_canon_sha256":"2a9724c9fb64e4ad19b0b1973dd923a317d0702eae0a8991d315f4b329ac1fda"},"schema_version":"1.0"},"canonical_sha256":"ba2c6753dca5400d66eb883c0f3977a552912d3b1b55d8d64500ce94190ac2c7","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T01:45:43.993490Z","signature_b64":"sgw8tzH/05ZKYw8v64YbYrWTLB0xQUcDQoaijsvmQ+1Ey1sQJVWcGwIE0ACGApkZf0zaS4TPaCXef11AHEyUAA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"ba2c6753dca5400d66eb883c0f3977a552912d3b1b55d8d64500ce94190ac2c7","last_reissued_at":"2026-05-18T01:45:43.992799Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T01:45:43.992799Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1312.5537","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:45:43Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"oNMp8BOCaJ44eHUsihm646M7KRhYdWHmYKF3bAzArmX8hWbioY81HDkis4eD1PKHT53WeLs4sglo2n1vYm+LBg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-29T21:32:10.603065Z"},"content_sha256":"ebb7436c95bb26645acc358b78d2b39527aad720a1fbc8b1c30bc29fb9aba2d2","schema_version":"1.0","event_id":"sha256:ebb7436c95bb26645acc358b78d2b39527aad720a1fbc8b1c30bc29fb9aba2d2"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2013:XIWGOU64UVAA2ZXLRA6A6OLXUV","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"RNA-based regulation: dynamics and response to perturbations of competing RNAs","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["cond-mat.dis-nn","cond-mat.stat-mech","q-bio.GN","q-bio.QM"],"primary_cat":"q-bio.MN","authors_text":"Andrea De Martino, Enzo Marinari, Matteo Figliuzzi","submitted_at":"2013-12-19T13:24:43Z","abstract_excerpt":"The observation that, through a titration mechanism, microRNAs (miRNAs) can act as mediators of effective interactions among their common targets (competing endogenous RNAs or ceRNAs) has brought forward the idea ('ceRNA hypothesis') that RNAs can regulate each other in extended 'cross-talk' networks. Such an ability might play a major role in post-transcriptional regulation (PTR) in shaping a cell's protein repertoire. Recent work focusing on the emergent properties of the cross-talk networks has emphasized the high flexibility and selectivity that may be achieved at stationarity. On the othe"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1312.5537","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:45:43Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"Np6zwbaBUoC5FIQVst+lkVsotre2WYkwkWZ0qghoEu84HQZG0c3CjIptImSciwQZQUKWwvtrfEOByqJF+kqGDQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-29T21:32:10.603726Z"},"content_sha256":"283db245f98382c38029763e4e8dfba02173fa69a66723279b0b6d7ad135ed88","schema_version":"1.0","event_id":"sha256:283db245f98382c38029763e4e8dfba02173fa69a66723279b0b6d7ad135ed88"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/XIWGOU64UVAA2ZXLRA6A6OLXUV/bundle.json","state_url":"https://pith.science/pith/XIWGOU64UVAA2ZXLRA6A6OLXUV/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/XIWGOU64UVAA2ZXLRA6A6OLXUV/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-05-29T21:32:10Z","links":{"resolver":"https://pith.science/pith/XIWGOU64UVAA2ZXLRA6A6OLXUV","bundle":"https://pith.science/pith/XIWGOU64UVAA2ZXLRA6A6OLXUV/bundle.json","state":"https://pith.science/pith/XIWGOU64UVAA2ZXLRA6A6OLXUV/state.json","well_known_bundle":"https://pith.science/.well-known/pith/XIWGOU64UVAA2ZXLRA6A6OLXUV/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2013:XIWGOU64UVAA2ZXLRA6A6OLXUV","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"2a9724c9fb64e4ad19b0b1973dd923a317d0702eae0a8991d315f4b329ac1fda","cross_cats_sorted":["cond-mat.dis-nn","cond-mat.stat-mech","q-bio.GN","q-bio.QM"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.MN","submitted_at":"2013-12-19T13:24:43Z","title_canon_sha256":"5f62e431e0946ed034ff199281e004045001b5c8392a4203b9fdd11c7f0f6fdc"},"schema_version":"1.0","source":{"id":"1312.5537","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1312.5537","created_at":"2026-05-18T01:45:43Z"},{"alias_kind":"arxiv_version","alias_value":"1312.5537v1","created_at":"2026-05-18T01:45:43Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1312.5537","created_at":"2026-05-18T01:45:43Z"},{"alias_kind":"pith_short_12","alias_value":"XIWGOU64UVAA","created_at":"2026-05-18T12:28:06Z"},{"alias_kind":"pith_short_16","alias_value":"XIWGOU64UVAA2ZXL","created_at":"2026-05-18T12:28:06Z"},{"alias_kind":"pith_short_8","alias_value":"XIWGOU64","created_at":"2026-05-18T12:28:06Z"}],"graph_snapshots":[{"event_id":"sha256:283db245f98382c38029763e4e8dfba02173fa69a66723279b0b6d7ad135ed88","target":"graph","created_at":"2026-05-18T01:45:43Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"The observation that, through a titration mechanism, microRNAs (miRNAs) can act as mediators of effective interactions among their common targets (competing endogenous RNAs or ceRNAs) has brought forward the idea ('ceRNA hypothesis') that RNAs can regulate each other in extended 'cross-talk' networks. Such an ability might play a major role in post-transcriptional regulation (PTR) in shaping a cell's protein repertoire. Recent work focusing on the emergent properties of the cross-talk networks has emphasized the high flexibility and selectivity that may be achieved at stationarity. On the othe","authors_text":"Andrea De Martino, Enzo Marinari, Matteo Figliuzzi","cross_cats":["cond-mat.dis-nn","cond-mat.stat-mech","q-bio.GN","q-bio.QM"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.MN","submitted_at":"2013-12-19T13:24:43Z","title":"RNA-based regulation: dynamics and response to perturbations of competing RNAs"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1312.5537","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:ebb7436c95bb26645acc358b78d2b39527aad720a1fbc8b1c30bc29fb9aba2d2","target":"record","created_at":"2026-05-18T01:45:43Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"2a9724c9fb64e4ad19b0b1973dd923a317d0702eae0a8991d315f4b329ac1fda","cross_cats_sorted":["cond-mat.dis-nn","cond-mat.stat-mech","q-bio.GN","q-bio.QM"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.MN","submitted_at":"2013-12-19T13:24:43Z","title_canon_sha256":"5f62e431e0946ed034ff199281e004045001b5c8392a4203b9fdd11c7f0f6fdc"},"schema_version":"1.0","source":{"id":"1312.5537","kind":"arxiv","version":1}},"canonical_sha256":"ba2c6753dca5400d66eb883c0f3977a552912d3b1b55d8d64500ce94190ac2c7","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"ba2c6753dca5400d66eb883c0f3977a552912d3b1b55d8d64500ce94190ac2c7","first_computed_at":"2026-05-18T01:45:43.992799Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T01:45:43.992799Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"sgw8tzH/05ZKYw8v64YbYrWTLB0xQUcDQoaijsvmQ+1Ey1sQJVWcGwIE0ACGApkZf0zaS4TPaCXef11AHEyUAA==","signature_status":"signed_v1","signed_at":"2026-05-18T01:45:43.993490Z","signed_message":"canonical_sha256_bytes"},"source_id":"1312.5537","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:ebb7436c95bb26645acc358b78d2b39527aad720a1fbc8b1c30bc29fb9aba2d2","sha256:283db245f98382c38029763e4e8dfba02173fa69a66723279b0b6d7ad135ed88"],"state_sha256":"ff97eea08015302722d1334d52f6fe3d2d37f2912fd440a255453990d8a8ca3f"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"Y+9DeLRqd/2cWEfVocN7RwTnv+AX5oiuN50hsQ1dQbma2QRe14p7GLrAIJ1yOOrNYNU4YkrENSmufpsOSwV1Dg==","signed_message":"bundle_sha256_bytes","signed_at":"2026-05-29T21:32:10.606363Z","bundle_sha256":"1d179bc8fff29c499eda719ad5daccafd2900f531b74311c02c72f110b030e54"}}