{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2020:XKW55OWUOI4IF34HMW3K5PMRXW","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"e853aff4999bf994e3dbf4f1ccecdce1ec5df664b22acf7d4ac15c70dab92dd8","cross_cats_sorted":["cs.CV","cs.LG","physics.med-ph"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"eess.IV","submitted_at":"2020-08-20T10:12:03Z","title_canon_sha256":"1443a764c2209481cae4453f5317e79d63a62cea3ce512fc68f2a20a46a2467c"},"schema_version":"1.0","source":{"id":"2008.08871","kind":"arxiv","version":2}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2008.08871","created_at":"2026-07-05T03:05:31Z"},{"alias_kind":"arxiv_version","alias_value":"2008.08871v2","created_at":"2026-07-05T03:05:31Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2008.08871","created_at":"2026-07-05T03:05:31Z"},{"alias_kind":"pith_short_12","alias_value":"XKW55OWUOI4I","created_at":"2026-07-05T03:05:31Z"},{"alias_kind":"pith_short_16","alias_value":"XKW55OWUOI4IF34H","created_at":"2026-07-05T03:05:31Z"},{"alias_kind":"pith_short_8","alias_value":"XKW55OWU","created_at":"2026-07-05T03:05:31Z"}],"graph_snapshots":[{"event_id":"sha256:5fd9fdeec5d7520b3a6cc7ce82b630106e5f24345c8def13f1af77a6d79a48e7","target":"graph","created_at":"2026-07-05T03:05:31Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2008.08871/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Pathology is practiced by visual inspection of histochemically stained slides. Most commonly, the hematoxylin and eosin (H&E) stain is used in the diagnostic workflow and it is the gold standard for cancer diagnosis. However, in many cases, especially for non-neoplastic diseases, additional \"special stains\" are used to provide different levels of contrast and color to tissue components and allow pathologists to get a clearer diagnostic picture. In this study, we demonstrate the utility of supervised learning-based computational stain transformation from H&E to different special stains (Masson'","authors_text":"Alexander Nobori, Anthony E. Sisk, Aydogan Ozcan, Jonathan E. Zuckerman, Kevin De Haan, Kuang-Yu Jen, Miguel F. P. Diaz, Rana Riahi, Sarah Zhang, Sofia Liou, Tairan Liu, W. Dean Wallace, Yair Rivenson, Yijie Zhang","cross_cats":["cs.CV","cs.LG","physics.med-ph"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"eess.IV","submitted_at":"2020-08-20T10:12:03Z","title":"Deep learning-based transformation of the H&E stain into special stains"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2008.08871","kind":"arxiv","version":2},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:5652cf15da1523cbf3c2c11f9caefe320f626031bd23073c6f7cbcbead48fd95","target":"record","created_at":"2026-07-05T03:05:31Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"e853aff4999bf994e3dbf4f1ccecdce1ec5df664b22acf7d4ac15c70dab92dd8","cross_cats_sorted":["cs.CV","cs.LG","physics.med-ph"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"eess.IV","submitted_at":"2020-08-20T10:12:03Z","title_canon_sha256":"1443a764c2209481cae4453f5317e79d63a62cea3ce512fc68f2a20a46a2467c"},"schema_version":"1.0","source":{"id":"2008.08871","kind":"arxiv","version":2}},"canonical_sha256":"baaddebad4723882ef8765b6aebd91bd8a49237ff45d524ba4a076644009f7e4","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"baaddebad4723882ef8765b6aebd91bd8a49237ff45d524ba4a076644009f7e4","first_computed_at":"2026-07-05T03:05:31.468726Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T03:05:31.468726Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"tVgv8yM0S9CeT4kjCvJtE+W+xSBkxfPtcz65SBZHrhLfTJrX77GLgeyyDGGBf7WHOnCXjtJDk30t14ID3q4eAA==","signature_status":"signed_v1","signed_at":"2026-07-05T03:05:31.469613Z","signed_message":"canonical_sha256_bytes"},"source_id":"2008.08871","source_kind":"arxiv","source_version":2}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:5652cf15da1523cbf3c2c11f9caefe320f626031bd23073c6f7cbcbead48fd95","sha256:5fd9fdeec5d7520b3a6cc7ce82b630106e5f24345c8def13f1af77a6d79a48e7"],"state_sha256":"9a5ef1693ede72b8d45844f13be35d031ec9117304d166948a0483bc5c5fcf19"}