{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2024:YA7RKP5C5SADQP37RW2GD4C2TB","short_pith_number":"pith:YA7RKP5C","canonical_record":{"source":{"id":"2411.18074","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/publicdomain/zero/1.0/","primary_cat":"physics.med-ph","submitted_at":"2024-11-27T05:56:38Z","cross_cats_sorted":[],"title_canon_sha256":"3fc6a03b36eb1d3cad304518cae1782ff0b92cfc97931f08379c3567b280f249","abstract_canon_sha256":"3018f70bc7f064905f06570a519c3cc64bb9c7fb3921c28591f7f9f152115adf"},"schema_version":"1.0"},"canonical_sha256":"c03f153fa2ec80383f7f8db461f05a9850994f97efcec6c0ee5a95411d1b7de3","source":{"kind":"arxiv","id":"2411.18074","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2411.18074","created_at":"2026-07-05T09:41:11Z"},{"alias_kind":"arxiv_version","alias_value":"2411.18074v1","created_at":"2026-07-05T09:41:11Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2411.18074","created_at":"2026-07-05T09:41:11Z"},{"alias_kind":"pith_short_12","alias_value":"YA7RKP5C5SAD","created_at":"2026-07-05T09:41:11Z"},{"alias_kind":"pith_short_16","alias_value":"YA7RKP5C5SADQP37","created_at":"2026-07-05T09:41:11Z"},{"alias_kind":"pith_short_8","alias_value":"YA7RKP5C","created_at":"2026-07-05T09:41:11Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2024:YA7RKP5C5SADQP37RW2GD4C2TB","target":"record","payload":{"canonical_record":{"source":{"id":"2411.18074","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/publicdomain/zero/1.0/","primary_cat":"physics.med-ph","submitted_at":"2024-11-27T05:56:38Z","cross_cats_sorted":[],"title_canon_sha256":"3fc6a03b36eb1d3cad304518cae1782ff0b92cfc97931f08379c3567b280f249","abstract_canon_sha256":"3018f70bc7f064905f06570a519c3cc64bb9c7fb3921c28591f7f9f152115adf"},"schema_version":"1.0"},"canonical_sha256":"c03f153fa2ec80383f7f8db461f05a9850994f97efcec6c0ee5a95411d1b7de3","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T09:41:11.410425Z","signature_b64":"74Sl9t25Bl38jaoBEIjBSp2Mm8IbZtephBNMz69XrGA9GDcoatscyeotmLXJK7zR/K+8z+nH2cmDROqyVWOnAg==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"c03f153fa2ec80383f7f8db461f05a9850994f97efcec6c0ee5a95411d1b7de3","last_reissued_at":"2026-07-05T09:41:11.409973Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T09:41:11.409973Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2411.18074","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T09:41:11Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"x8IN1dOKMMFVYo3JcTqxUL338ZvaKPTxCqEdshtGbhuECHAzv343ML0ViwWeXTiLiDUcQdrhu2lLbiPPH4MuAg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-12T23:30:25.236914Z"},"content_sha256":"bde0d7ec3564c5b1a56bd69855cf57a8caf2301df65ac4e9301f66fd831106fe","schema_version":"1.0","event_id":"sha256:bde0d7ec3564c5b1a56bd69855cf57a8caf2301df65ac4e9301f66fd831106fe"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2024:YA7RKP5C5SADQP37RW2GD4C2TB","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Development and experimental validation of an in-house treatment planning system with greedy energy layer optimization for fast IMPT","license":"http://creativecommons.org/publicdomain/zero/1.0/","headline":"","cross_cats":[],"primary_cat":"physics.med-ph","authors_text":"Aoxiang Wang, Hao Gao, Jufri Setianegara, Peng Xiao, Qingguo Xie, Ya-Nan Zhu, YuTing Lin","submitted_at":"2024-11-27T05:56:38Z","abstract_excerpt":"Background: Intensity-modulated proton therapy (IMPT) using pencil beam technique scans tumor in a layer by layer, then spot by spot manner. It can provide highly conformal dose to tumor targets and spare nearby organs-at-risk (OAR). Fast delivery of IMPT can improve patient comfort and reduce motion-induced uncertainties. Since energy layer switching time dominants the plan delivery time, reducing the number of energy layers is important for improving delivery efficiency. Although various energy layer optimization (ELO) methods exist, they are rarely experimentally validated or clinically imp"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2411.18074","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2411.18074/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T09:41:11Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"64VK4yO3PFGkxGLO+8fhvrFJCLWQzr2038GlAODl+o41h+TGV0AIFNsMj2pOl0vVH28RtrhdM34HdcpFSMD7BA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-12T23:30:25.237445Z"},"content_sha256":"2a9645142bf94f85deff414ce77e68ce14f389997177c0bdc4a27432847b5875","schema_version":"1.0","event_id":"sha256:2a9645142bf94f85deff414ce77e68ce14f389997177c0bdc4a27432847b5875"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/YA7RKP5C5SADQP37RW2GD4C2TB/bundle.json","state_url":"https://pith.science/pith/YA7RKP5C5SADQP37RW2GD4C2TB/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/YA7RKP5C5SADQP37RW2GD4C2TB/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-08-12T23:30:25Z","links":{"resolver":"https://pith.science/pith/YA7RKP5C5SADQP37RW2GD4C2TB","bundle":"https://pith.science/pith/YA7RKP5C5SADQP37RW2GD4C2TB/bundle.json","state":"https://pith.science/pith/YA7RKP5C5SADQP37RW2GD4C2TB/state.json","well_known_bundle":"https://pith.science/.well-known/pith/YA7RKP5C5SADQP37RW2GD4C2TB/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2024:YA7RKP5C5SADQP37RW2GD4C2TB","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"3018f70bc7f064905f06570a519c3cc64bb9c7fb3921c28591f7f9f152115adf","cross_cats_sorted":[],"license":"http://creativecommons.org/publicdomain/zero/1.0/","primary_cat":"physics.med-ph","submitted_at":"2024-11-27T05:56:38Z","title_canon_sha256":"3fc6a03b36eb1d3cad304518cae1782ff0b92cfc97931f08379c3567b280f249"},"schema_version":"1.0","source":{"id":"2411.18074","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2411.18074","created_at":"2026-07-05T09:41:11Z"},{"alias_kind":"arxiv_version","alias_value":"2411.18074v1","created_at":"2026-07-05T09:41:11Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2411.18074","created_at":"2026-07-05T09:41:11Z"},{"alias_kind":"pith_short_12","alias_value":"YA7RKP5C5SAD","created_at":"2026-07-05T09:41:11Z"},{"alias_kind":"pith_short_16","alias_value":"YA7RKP5C5SADQP37","created_at":"2026-07-05T09:41:11Z"},{"alias_kind":"pith_short_8","alias_value":"YA7RKP5C","created_at":"2026-07-05T09:41:11Z"}],"graph_snapshots":[{"event_id":"sha256:2a9645142bf94f85deff414ce77e68ce14f389997177c0bdc4a27432847b5875","target":"graph","created_at":"2026-07-05T09:41:11Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2411.18074/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Background: Intensity-modulated proton therapy (IMPT) using pencil beam technique scans tumor in a layer by layer, then spot by spot manner. It can provide highly conformal dose to tumor targets and spare nearby organs-at-risk (OAR). Fast delivery of IMPT can improve patient comfort and reduce motion-induced uncertainties. Since energy layer switching time dominants the plan delivery time, reducing the number of energy layers is important for improving delivery efficiency. Although various energy layer optimization (ELO) methods exist, they are rarely experimentally validated or clinically imp","authors_text":"Aoxiang Wang, Hao Gao, Jufri Setianegara, Peng Xiao, Qingguo Xie, Ya-Nan Zhu, YuTing Lin","cross_cats":[],"headline":"","license":"http://creativecommons.org/publicdomain/zero/1.0/","primary_cat":"physics.med-ph","submitted_at":"2024-11-27T05:56:38Z","title":"Development and experimental validation of an in-house treatment planning system with greedy energy layer optimization for fast IMPT"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2411.18074","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:bde0d7ec3564c5b1a56bd69855cf57a8caf2301df65ac4e9301f66fd831106fe","target":"record","created_at":"2026-07-05T09:41:11Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"3018f70bc7f064905f06570a519c3cc64bb9c7fb3921c28591f7f9f152115adf","cross_cats_sorted":[],"license":"http://creativecommons.org/publicdomain/zero/1.0/","primary_cat":"physics.med-ph","submitted_at":"2024-11-27T05:56:38Z","title_canon_sha256":"3fc6a03b36eb1d3cad304518cae1782ff0b92cfc97931f08379c3567b280f249"},"schema_version":"1.0","source":{"id":"2411.18074","kind":"arxiv","version":1}},"canonical_sha256":"c03f153fa2ec80383f7f8db461f05a9850994f97efcec6c0ee5a95411d1b7de3","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"c03f153fa2ec80383f7f8db461f05a9850994f97efcec6c0ee5a95411d1b7de3","first_computed_at":"2026-07-05T09:41:11.409973Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T09:41:11.409973Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"74Sl9t25Bl38jaoBEIjBSp2Mm8IbZtephBNMz69XrGA9GDcoatscyeotmLXJK7zR/K+8z+nH2cmDROqyVWOnAg==","signature_status":"signed_v1","signed_at":"2026-07-05T09:41:11.410425Z","signed_message":"canonical_sha256_bytes"},"source_id":"2411.18074","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:bde0d7ec3564c5b1a56bd69855cf57a8caf2301df65ac4e9301f66fd831106fe","sha256:2a9645142bf94f85deff414ce77e68ce14f389997177c0bdc4a27432847b5875"],"state_sha256":"09fc12b778a0c0bb5c49efa7ad181c6128811c50253c3e28c10a2f9e3116743f"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"to5spbUiJrKCtqCsrg2TZLqxhfkXwPvglYRyEmP5CsU9SudI5EppkOkDnfovFhZNGILjFV1qJrXYKm91LECKCQ==","signed_message":"bundle_sha256_bytes","signed_at":"2026-08-12T23:30:25.242351Z","bundle_sha256":"907f0d1839eb017611a08bb419cbd878125c3b2be498d913cf7c3841cd6bf4a9"}}