{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2010:YAGMSFTWXTZ4DS655TU3OJ5H7M","short_pith_number":"pith:YAGMSFTW","canonical_record":{"source":{"id":"1011.0370","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.CB","submitted_at":"2010-11-01T16:28:18Z","cross_cats_sorted":["physics.bio-ph"],"title_canon_sha256":"23dc0aee03bd67745791004a5b93650ab8ae9748f20dc7ec8ded6b4ddeeeeca3","abstract_canon_sha256":"d26edde89ccfa5fa629f63e632b85bd8c47c6725de3ddba06a58b0eb3ace10fb"},"schema_version":"1.0"},"canonical_sha256":"c00cc91676bcf3c1cbddece9b727a7fb11725fda3aa651ca4ef006e92d2bf4b7","source":{"kind":"arxiv","id":"1011.0370","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1011.0370","created_at":"2026-05-18T04:37:23Z"},{"alias_kind":"arxiv_version","alias_value":"1011.0370v1","created_at":"2026-05-18T04:37:23Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1011.0370","created_at":"2026-05-18T04:37:23Z"},{"alias_kind":"pith_short_12","alias_value":"YAGMSFTWXTZ4","created_at":"2026-05-18T12:26:17Z"},{"alias_kind":"pith_short_16","alias_value":"YAGMSFTWXTZ4DS65","created_at":"2026-05-18T12:26:17Z"},{"alias_kind":"pith_short_8","alias_value":"YAGMSFTW","created_at":"2026-05-18T12:26:17Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2010:YAGMSFTWXTZ4DS655TU3OJ5H7M","target":"record","payload":{"canonical_record":{"source":{"id":"1011.0370","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.CB","submitted_at":"2010-11-01T16:28:18Z","cross_cats_sorted":["physics.bio-ph"],"title_canon_sha256":"23dc0aee03bd67745791004a5b93650ab8ae9748f20dc7ec8ded6b4ddeeeeca3","abstract_canon_sha256":"d26edde89ccfa5fa629f63e632b85bd8c47c6725de3ddba06a58b0eb3ace10fb"},"schema_version":"1.0"},"canonical_sha256":"c00cc91676bcf3c1cbddece9b727a7fb11725fda3aa651ca4ef006e92d2bf4b7","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T04:37:23.330135Z","signature_b64":"eaND7/OgXHLZgculUBqSny/woyM2xI5o5u2O7JJAHlOew+TbZdfTiXnkp4VEtP2Ds9aq6zuUyYxXWVfUBhieAA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"c00cc91676bcf3c1cbddece9b727a7fb11725fda3aa651ca4ef006e92d2bf4b7","last_reissued_at":"2026-05-18T04:37:23.329727Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T04:37:23.329727Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1011.0370","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T04:37:23Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"dtM9FtRnf52tFRsaBoRzsAOpoWCIH6hcr9OUG1K702H+0TrPGPvCpvlYXwCXfdJBZnUWUF0ZwimMUsyneTqkAQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-04T03:58:20.414843Z"},"content_sha256":"0006a0e76b7bee69bff5b4c21ccd0e2604924871c9eb373e9f79fbbc6f14db6a","schema_version":"1.0","event_id":"sha256:0006a0e76b7bee69bff5b4c21ccd0e2604924871c9eb373e9f79fbbc6f14db6a"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2010:YAGMSFTWXTZ4DS655TU3OJ5H7M","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"The zipper mechanism in phagocytosis: energetic requirements and variability in phagocytic cup shape","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["physics.bio-ph"],"primary_cat":"q-bio.CB","authors_text":"Anna E. Dart, George Tzircotis, Robert G. Endres, Sylvain Tollis","submitted_at":"2010-11-01T16:28:18Z","abstract_excerpt":"Phagocytosis is the fundamental cellular process by which eukaryotic cells bind and engulf particles by their cell membrane. Particle engulfment involves particle recognition by cell-surface receptors, signaling and remodeling of the actin cytoskeleton to guide the membrane around the particle in a zipper-like fashion. Despite the signaling complexity, phagocytosis also depends strongly on biophysical parameters, such as particle shape, and the need for actin-driven force generation remains poorly understood. Here, we propose a novel, three-dimensional and stochastic biophysical model of phago"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1011.0370","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T04:37:23Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"6LRgLhyFu2Q5gxtc/1N+p3kRvzeZ/2gXUsHNFTW4o5e6l2zg6EYVMHlMl1g7zMdRRkdGXqY/vc7U/wGUgT85Dw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-04T03:58:20.415367Z"},"content_sha256":"faaee0fea80ada3e85a7347e259779d084335adf0f36c2390be380ff26853c4a","schema_version":"1.0","event_id":"sha256:faaee0fea80ada3e85a7347e259779d084335adf0f36c2390be380ff26853c4a"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/YAGMSFTWXTZ4DS655TU3OJ5H7M/bundle.json","state_url":"https://pith.science/pith/YAGMSFTWXTZ4DS655TU3OJ5H7M/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/YAGMSFTWXTZ4DS655TU3OJ5H7M/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-04T03:58:20Z","links":{"resolver":"https://pith.science/pith/YAGMSFTWXTZ4DS655TU3OJ5H7M","bundle":"https://pith.science/pith/YAGMSFTWXTZ4DS655TU3OJ5H7M/bundle.json","state":"https://pith.science/pith/YAGMSFTWXTZ4DS655TU3OJ5H7M/state.json","well_known_bundle":"https://pith.science/.well-known/pith/YAGMSFTWXTZ4DS655TU3OJ5H7M/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2010:YAGMSFTWXTZ4DS655TU3OJ5H7M","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"d26edde89ccfa5fa629f63e632b85bd8c47c6725de3ddba06a58b0eb3ace10fb","cross_cats_sorted":["physics.bio-ph"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.CB","submitted_at":"2010-11-01T16:28:18Z","title_canon_sha256":"23dc0aee03bd67745791004a5b93650ab8ae9748f20dc7ec8ded6b4ddeeeeca3"},"schema_version":"1.0","source":{"id":"1011.0370","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1011.0370","created_at":"2026-05-18T04:37:23Z"},{"alias_kind":"arxiv_version","alias_value":"1011.0370v1","created_at":"2026-05-18T04:37:23Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1011.0370","created_at":"2026-05-18T04:37:23Z"},{"alias_kind":"pith_short_12","alias_value":"YAGMSFTWXTZ4","created_at":"2026-05-18T12:26:17Z"},{"alias_kind":"pith_short_16","alias_value":"YAGMSFTWXTZ4DS65","created_at":"2026-05-18T12:26:17Z"},{"alias_kind":"pith_short_8","alias_value":"YAGMSFTW","created_at":"2026-05-18T12:26:17Z"}],"graph_snapshots":[{"event_id":"sha256:faaee0fea80ada3e85a7347e259779d084335adf0f36c2390be380ff26853c4a","target":"graph","created_at":"2026-05-18T04:37:23Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Phagocytosis is the fundamental cellular process by which eukaryotic cells bind and engulf particles by their cell membrane. Particle engulfment involves particle recognition by cell-surface receptors, signaling and remodeling of the actin cytoskeleton to guide the membrane around the particle in a zipper-like fashion. Despite the signaling complexity, phagocytosis also depends strongly on biophysical parameters, such as particle shape, and the need for actin-driven force generation remains poorly understood. Here, we propose a novel, three-dimensional and stochastic biophysical model of phago","authors_text":"Anna E. Dart, George Tzircotis, Robert G. Endres, Sylvain Tollis","cross_cats":["physics.bio-ph"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.CB","submitted_at":"2010-11-01T16:28:18Z","title":"The zipper mechanism in phagocytosis: energetic requirements and variability in phagocytic cup shape"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1011.0370","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:0006a0e76b7bee69bff5b4c21ccd0e2604924871c9eb373e9f79fbbc6f14db6a","target":"record","created_at":"2026-05-18T04:37:23Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"d26edde89ccfa5fa629f63e632b85bd8c47c6725de3ddba06a58b0eb3ace10fb","cross_cats_sorted":["physics.bio-ph"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.CB","submitted_at":"2010-11-01T16:28:18Z","title_canon_sha256":"23dc0aee03bd67745791004a5b93650ab8ae9748f20dc7ec8ded6b4ddeeeeca3"},"schema_version":"1.0","source":{"id":"1011.0370","kind":"arxiv","version":1}},"canonical_sha256":"c00cc91676bcf3c1cbddece9b727a7fb11725fda3aa651ca4ef006e92d2bf4b7","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"c00cc91676bcf3c1cbddece9b727a7fb11725fda3aa651ca4ef006e92d2bf4b7","first_computed_at":"2026-05-18T04:37:23.329727Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T04:37:23.329727Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"eaND7/OgXHLZgculUBqSny/woyM2xI5o5u2O7JJAHlOew+TbZdfTiXnkp4VEtP2Ds9aq6zuUyYxXWVfUBhieAA==","signature_status":"signed_v1","signed_at":"2026-05-18T04:37:23.330135Z","signed_message":"canonical_sha256_bytes"},"source_id":"1011.0370","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:0006a0e76b7bee69bff5b4c21ccd0e2604924871c9eb373e9f79fbbc6f14db6a","sha256:faaee0fea80ada3e85a7347e259779d084335adf0f36c2390be380ff26853c4a"],"state_sha256":"ab1651da50b5142f7466465c725bb7062961200e1c288000a608a352497b4ed2"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"PIcz8XXC8Y9xueyZTBk2m+WmP69W99EUmQmiUy/wQj+ArV4wVNbpn08X1q33qwp31PxFeqcfWbEZGIDLrRtbBQ==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-04T03:58:20.418199Z","bundle_sha256":"60e44d40dbbb96539b672ca9b102521522cf34e82edb02579aeb674481de04d8"}}