{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2018:YHNCAIQLL7PZLON7JZ6ZVHAGST","short_pith_number":"pith:YHNCAIQL","canonical_record":{"source":{"id":"1805.09121","kind":"arxiv","version":3},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.med-ph","submitted_at":"2018-05-23T13:21:42Z","cross_cats_sorted":[],"title_canon_sha256":"540da167e24edbfc1d634d3e17f83323c419ac894d1fdfcaf712d96ee29eb783","abstract_canon_sha256":"ef18430eb8ffcc13f517339ac2bfe2e3101fad66a73797f3db2157d2c4066fbf"},"schema_version":"1.0"},"canonical_sha256":"c1da20220b5fdf95b9bf4e7d9a9c0694f745c922ac420146c8194e8e6cfbbfca","source":{"kind":"arxiv","id":"1805.09121","version":3},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1805.09121","created_at":"2026-05-17T23:54:54Z"},{"alias_kind":"arxiv_version","alias_value":"1805.09121v3","created_at":"2026-05-17T23:54:54Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1805.09121","created_at":"2026-05-17T23:54:54Z"},{"alias_kind":"pith_short_12","alias_value":"YHNCAIQLL7PZ","created_at":"2026-05-18T12:33:04Z"},{"alias_kind":"pith_short_16","alias_value":"YHNCAIQLL7PZLON7","created_at":"2026-05-18T12:33:04Z"},{"alias_kind":"pith_short_8","alias_value":"YHNCAIQL","created_at":"2026-05-18T12:33:04Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2018:YHNCAIQLL7PZLON7JZ6ZVHAGST","target":"record","payload":{"canonical_record":{"source":{"id":"1805.09121","kind":"arxiv","version":3},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.med-ph","submitted_at":"2018-05-23T13:21:42Z","cross_cats_sorted":[],"title_canon_sha256":"540da167e24edbfc1d634d3e17f83323c419ac894d1fdfcaf712d96ee29eb783","abstract_canon_sha256":"ef18430eb8ffcc13f517339ac2bfe2e3101fad66a73797f3db2157d2c4066fbf"},"schema_version":"1.0"},"canonical_sha256":"c1da20220b5fdf95b9bf4e7d9a9c0694f745c922ac420146c8194e8e6cfbbfca","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-17T23:54:54.299357Z","signature_b64":"AU9XxDP3Eg1ZNnFO+URiWzzh+P7Lljk0PTRXgOMlf4lPFjJHvgE/GW5phmfDuChkPtkfOVzzqpZYxY6Y5JzwAQ==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"c1da20220b5fdf95b9bf4e7d9a9c0694f745c922ac420146c8194e8e6cfbbfca","last_reissued_at":"2026-05-17T23:54:54.298716Z","signature_status":"signed_v1","first_computed_at":"2026-05-17T23:54:54.298716Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1805.09121","source_version":3,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-17T23:54:54Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"m8lA2AIhm3fyRdHNM+iiSuD6ZUbQrSlAQelz6RiDvlU419f1sllMnUbkkLccz30O9QaP+d96jgreVnADdlm6Dw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-03T12:50:12.874529Z"},"content_sha256":"5b134a71dce4e3841aa9197d4ed99e3771eb1fabadb418d8ae27bddef03d6ba0","schema_version":"1.0","event_id":"sha256:5b134a71dce4e3841aa9197d4ed99e3771eb1fabadb418d8ae27bddef03d6ba0"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2018:YHNCAIQLL7PZLON7JZ6ZVHAGST","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Estimating blood pressure trends and the nocturnal dip from photoplethysmograph","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"physics.med-ph","authors_text":"Cybele CP Wong, Koen de Groot, Mustafa Radha, Nadja Kobold, Nathalie Velthoven, Nikita Rajani, Nikolaos Mastellos, Pedro Fonseca, Petra A Wark, Reinder Haakma, Ronald M Aarts, Valentina Vos","submitted_at":"2018-05-23T13:21:42Z","abstract_excerpt":"Objective: Evaluate a method for the estimation of the nocturnal systolic blood pressure (SBP) dip from 24-hour blood pressure trends using a wrist-worn photoplethysmography (PPG) sensor and a deep neural network in free-living individuals, comparing the deep neural network to traditional machine learning and non-machine learning baselines.\n  Approach: A wrist-worn PPG sensor was worn by 106 healthy individuals for 226 days during which 5111 reference values for blood pressure (BP) were obtained with a 24-hour ambulatory BP monitor and matched with the PPG sensor data. Features based on heart "},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1805.09121","kind":"arxiv","version":3},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-17T23:54:54Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"kzS7RI82QTGBTsKCgpjTqrbRCMcuWIKcac5Z6EolxEHvHVy8liMfBmPpAaCxHG3i9xqyY8y08GYo+4oCOY0fCg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-03T12:50:12.874878Z"},"content_sha256":"9e6c1e1310f120aeb7911a26b13203b972594c300e69687412b0e2ded2ac9b00","schema_version":"1.0","event_id":"sha256:9e6c1e1310f120aeb7911a26b13203b972594c300e69687412b0e2ded2ac9b00"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/YHNCAIQLL7PZLON7JZ6ZVHAGST/bundle.json","state_url":"https://pith.science/pith/YHNCAIQLL7PZLON7JZ6ZVHAGST/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/YHNCAIQLL7PZLON7JZ6ZVHAGST/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-03T12:50:12Z","links":{"resolver":"https://pith.science/pith/YHNCAIQLL7PZLON7JZ6ZVHAGST","bundle":"https://pith.science/pith/YHNCAIQLL7PZLON7JZ6ZVHAGST/bundle.json","state":"https://pith.science/pith/YHNCAIQLL7PZLON7JZ6ZVHAGST/state.json","well_known_bundle":"https://pith.science/.well-known/pith/YHNCAIQLL7PZLON7JZ6ZVHAGST/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2018:YHNCAIQLL7PZLON7JZ6ZVHAGST","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"ef18430eb8ffcc13f517339ac2bfe2e3101fad66a73797f3db2157d2c4066fbf","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.med-ph","submitted_at":"2018-05-23T13:21:42Z","title_canon_sha256":"540da167e24edbfc1d634d3e17f83323c419ac894d1fdfcaf712d96ee29eb783"},"schema_version":"1.0","source":{"id":"1805.09121","kind":"arxiv","version":3}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1805.09121","created_at":"2026-05-17T23:54:54Z"},{"alias_kind":"arxiv_version","alias_value":"1805.09121v3","created_at":"2026-05-17T23:54:54Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1805.09121","created_at":"2026-05-17T23:54:54Z"},{"alias_kind":"pith_short_12","alias_value":"YHNCAIQLL7PZ","created_at":"2026-05-18T12:33:04Z"},{"alias_kind":"pith_short_16","alias_value":"YHNCAIQLL7PZLON7","created_at":"2026-05-18T12:33:04Z"},{"alias_kind":"pith_short_8","alias_value":"YHNCAIQL","created_at":"2026-05-18T12:33:04Z"}],"graph_snapshots":[{"event_id":"sha256:9e6c1e1310f120aeb7911a26b13203b972594c300e69687412b0e2ded2ac9b00","target":"graph","created_at":"2026-05-17T23:54:54Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Objective: Evaluate a method for the estimation of the nocturnal systolic blood pressure (SBP) dip from 24-hour blood pressure trends using a wrist-worn photoplethysmography (PPG) sensor and a deep neural network in free-living individuals, comparing the deep neural network to traditional machine learning and non-machine learning baselines.\n  Approach: A wrist-worn PPG sensor was worn by 106 healthy individuals for 226 days during which 5111 reference values for blood pressure (BP) were obtained with a 24-hour ambulatory BP monitor and matched with the PPG sensor data. Features based on heart ","authors_text":"Cybele CP Wong, Koen de Groot, Mustafa Radha, Nadja Kobold, Nathalie Velthoven, Nikita Rajani, Nikolaos Mastellos, Pedro Fonseca, Petra A Wark, Reinder Haakma, Ronald M Aarts, Valentina Vos","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.med-ph","submitted_at":"2018-05-23T13:21:42Z","title":"Estimating blood pressure trends and the nocturnal dip from photoplethysmograph"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1805.09121","kind":"arxiv","version":3},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:5b134a71dce4e3841aa9197d4ed99e3771eb1fabadb418d8ae27bddef03d6ba0","target":"record","created_at":"2026-05-17T23:54:54Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"ef18430eb8ffcc13f517339ac2bfe2e3101fad66a73797f3db2157d2c4066fbf","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.med-ph","submitted_at":"2018-05-23T13:21:42Z","title_canon_sha256":"540da167e24edbfc1d634d3e17f83323c419ac894d1fdfcaf712d96ee29eb783"},"schema_version":"1.0","source":{"id":"1805.09121","kind":"arxiv","version":3}},"canonical_sha256":"c1da20220b5fdf95b9bf4e7d9a9c0694f745c922ac420146c8194e8e6cfbbfca","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"c1da20220b5fdf95b9bf4e7d9a9c0694f745c922ac420146c8194e8e6cfbbfca","first_computed_at":"2026-05-17T23:54:54.298716Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-17T23:54:54.298716Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"AU9XxDP3Eg1ZNnFO+URiWzzh+P7Lljk0PTRXgOMlf4lPFjJHvgE/GW5phmfDuChkPtkfOVzzqpZYxY6Y5JzwAQ==","signature_status":"signed_v1","signed_at":"2026-05-17T23:54:54.299357Z","signed_message":"canonical_sha256_bytes"},"source_id":"1805.09121","source_kind":"arxiv","source_version":3}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:5b134a71dce4e3841aa9197d4ed99e3771eb1fabadb418d8ae27bddef03d6ba0","sha256:9e6c1e1310f120aeb7911a26b13203b972594c300e69687412b0e2ded2ac9b00"],"state_sha256":"00665927e38557ecb637cf62b007c55d76bf4c8c38b0d00ad2d2dc9f2c752bff"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"Ksznz6jPgjXSpqybPJ39qFBzAj5qP2o5f/hzcyJYfFFyx1A5HgoEue613ONzWmznHOmhKYcDF+Qze/rwKWPDBg==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-03T12:50:12.876938Z","bundle_sha256":"cb6f7c547b5432cf35546d073f2b0f0859d63e29323626deeda94d4badb49a65"}}