{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2024:YHVNZK4GNOPKUMAWQ53POGS2LH","short_pith_number":"pith:YHVNZK4G","canonical_record":{"source":{"id":"2410.14612","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cs.CV","submitted_at":"2024-10-18T17:05:03Z","cross_cats_sorted":["q-bio.CB"],"title_canon_sha256":"f3939455cd98e1b3b3438e0933487b811dbf88f59db2f8549c3fdd044692fa0d","abstract_canon_sha256":"92cba6348af9cf336c456ecaf902047a45f122fab7c166558f4fdfa93d656f30"},"schema_version":"1.0"},"canonical_sha256":"c1eadcab866b9eaa30168776f71a5a59fcc8fea2d7283eb2a737a0718c208cf0","source":{"kind":"arxiv","id":"2410.14612","version":2},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2410.14612","created_at":"2026-07-05T09:47:35Z"},{"alias_kind":"arxiv_version","alias_value":"2410.14612v2","created_at":"2026-07-05T09:47:35Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2410.14612","created_at":"2026-07-05T09:47:35Z"},{"alias_kind":"pith_short_12","alias_value":"YHVNZK4GNOPK","created_at":"2026-07-05T09:47:35Z"},{"alias_kind":"pith_short_16","alias_value":"YHVNZK4GNOPKUMAW","created_at":"2026-07-05T09:47:35Z"},{"alias_kind":"pith_short_8","alias_value":"YHVNZK4G","created_at":"2026-07-05T09:47:35Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2024:YHVNZK4GNOPKUMAWQ53POGS2LH","target":"record","payload":{"canonical_record":{"source":{"id":"2410.14612","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cs.CV","submitted_at":"2024-10-18T17:05:03Z","cross_cats_sorted":["q-bio.CB"],"title_canon_sha256":"f3939455cd98e1b3b3438e0933487b811dbf88f59db2f8549c3fdd044692fa0d","abstract_canon_sha256":"92cba6348af9cf336c456ecaf902047a45f122fab7c166558f4fdfa93d656f30"},"schema_version":"1.0"},"canonical_sha256":"c1eadcab866b9eaa30168776f71a5a59fcc8fea2d7283eb2a737a0718c208cf0","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T09:47:35.539207Z","signature_b64":"EtT0OhPH7T1HqFQ96d8CsMVZXdh2eUtNfobIxQs2rgdj+uWI3nq6wpWvjTIIRV60UttDTx9CYGz46cmPKyV0BA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"c1eadcab866b9eaa30168776f71a5a59fcc8fea2d7283eb2a737a0718c208cf0","last_reissued_at":"2026-07-05T09:47:35.538709Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T09:47:35.538709Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2410.14612","source_version":2,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T09:47:35Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"RUtcSVrAEZmPE6Wn2Wpx+316s8aYdFRzAsOG9vQrMsrJDSkeJfWSkAGpag7+TRcK9KUiszD1HNHkim1I6HPyDQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-04T08:55:04.553764Z"},"content_sha256":"d495f60c8f7ea8fce3b72d5fdc6f45f73f80193c9ebe4e9f760a6cce1a4f6b36","schema_version":"1.0","event_id":"sha256:d495f60c8f7ea8fce3b72d5fdc6f45f73f80193c9ebe4e9f760a6cce1a4f6b36"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2024:YHVNZK4GNOPKUMAWQ53POGS2LH","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"MultiOrg: A Multi-rater Organoid-detection Dataset","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["q-bio.CB"],"primary_cat":"cs.CV","authors_text":"Carina Steinchen, Christina Bukas, Fenja See, Florian Kofler, Gerald Burgstaller, Gowtham Boosarpu, Harshavardhan Subramanian, Ivan Ezhov, Mareike Lehmann, Marie Piraud, Sara Asgharpour","submitted_at":"2024-10-18T17:05:03Z","abstract_excerpt":"High-throughput image analysis in the biomedical domain has gained significant attention in recent years, driving advancements in drug discovery, disease prediction, and personalized medicine. Organoids, specifically, are an active area of research, providing excellent models for human organs and their functions. Automating the quantification of organoids in microscopy images would provide an effective solution to overcome substantial manual quantification bottlenecks, particularly in high-throughput image analysis. However, there is a notable lack of open biomedical datasets, in contrast to o"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2410.14612","kind":"arxiv","version":2},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2410.14612/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T09:47:35Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"G3Uu9Lpzv7aXHheG2Q6QeFP0T3NZggDrIFi5mTUVqnCN/ZYInPk5vZVKhmpm9Ucmnw85z2lT9sNiM6HCXcdrBA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-04T08:55:04.554724Z"},"content_sha256":"5af8ad135b3a24f3138e86e892462ec3393c333283ef0d8065e48c112a6b946b","schema_version":"1.0","event_id":"sha256:5af8ad135b3a24f3138e86e892462ec3393c333283ef0d8065e48c112a6b946b"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/YHVNZK4GNOPKUMAWQ53POGS2LH/bundle.json","state_url":"https://pith.science/pith/YHVNZK4GNOPKUMAWQ53POGS2LH/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/YHVNZK4GNOPKUMAWQ53POGS2LH/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-08-04T08:55:04Z","links":{"resolver":"https://pith.science/pith/YHVNZK4GNOPKUMAWQ53POGS2LH","bundle":"https://pith.science/pith/YHVNZK4GNOPKUMAWQ53POGS2LH/bundle.json","state":"https://pith.science/pith/YHVNZK4GNOPKUMAWQ53POGS2LH/state.json","well_known_bundle":"https://pith.science/.well-known/pith/YHVNZK4GNOPKUMAWQ53POGS2LH/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2024:YHVNZK4GNOPKUMAWQ53POGS2LH","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"92cba6348af9cf336c456ecaf902047a45f122fab7c166558f4fdfa93d656f30","cross_cats_sorted":["q-bio.CB"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cs.CV","submitted_at":"2024-10-18T17:05:03Z","title_canon_sha256":"f3939455cd98e1b3b3438e0933487b811dbf88f59db2f8549c3fdd044692fa0d"},"schema_version":"1.0","source":{"id":"2410.14612","kind":"arxiv","version":2}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2410.14612","created_at":"2026-07-05T09:47:35Z"},{"alias_kind":"arxiv_version","alias_value":"2410.14612v2","created_at":"2026-07-05T09:47:35Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2410.14612","created_at":"2026-07-05T09:47:35Z"},{"alias_kind":"pith_short_12","alias_value":"YHVNZK4GNOPK","created_at":"2026-07-05T09:47:35Z"},{"alias_kind":"pith_short_16","alias_value":"YHVNZK4GNOPKUMAW","created_at":"2026-07-05T09:47:35Z"},{"alias_kind":"pith_short_8","alias_value":"YHVNZK4G","created_at":"2026-07-05T09:47:35Z"}],"graph_snapshots":[{"event_id":"sha256:5af8ad135b3a24f3138e86e892462ec3393c333283ef0d8065e48c112a6b946b","target":"graph","created_at":"2026-07-05T09:47:35Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2410.14612/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"High-throughput image analysis in the biomedical domain has gained significant attention in recent years, driving advancements in drug discovery, disease prediction, and personalized medicine. Organoids, specifically, are an active area of research, providing excellent models for human organs and their functions. Automating the quantification of organoids in microscopy images would provide an effective solution to overcome substantial manual quantification bottlenecks, particularly in high-throughput image analysis. However, there is a notable lack of open biomedical datasets, in contrast to o","authors_text":"Carina Steinchen, Christina Bukas, Fenja See, Florian Kofler, Gerald Burgstaller, Gowtham Boosarpu, Harshavardhan Subramanian, Ivan Ezhov, Mareike Lehmann, Marie Piraud, Sara Asgharpour","cross_cats":["q-bio.CB"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cs.CV","submitted_at":"2024-10-18T17:05:03Z","title":"MultiOrg: A Multi-rater Organoid-detection Dataset"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2410.14612","kind":"arxiv","version":2},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:d495f60c8f7ea8fce3b72d5fdc6f45f73f80193c9ebe4e9f760a6cce1a4f6b36","target":"record","created_at":"2026-07-05T09:47:35Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"92cba6348af9cf336c456ecaf902047a45f122fab7c166558f4fdfa93d656f30","cross_cats_sorted":["q-bio.CB"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cs.CV","submitted_at":"2024-10-18T17:05:03Z","title_canon_sha256":"f3939455cd98e1b3b3438e0933487b811dbf88f59db2f8549c3fdd044692fa0d"},"schema_version":"1.0","source":{"id":"2410.14612","kind":"arxiv","version":2}},"canonical_sha256":"c1eadcab866b9eaa30168776f71a5a59fcc8fea2d7283eb2a737a0718c208cf0","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"c1eadcab866b9eaa30168776f71a5a59fcc8fea2d7283eb2a737a0718c208cf0","first_computed_at":"2026-07-05T09:47:35.538709Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T09:47:35.538709Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"EtT0OhPH7T1HqFQ96d8CsMVZXdh2eUtNfobIxQs2rgdj+uWI3nq6wpWvjTIIRV60UttDTx9CYGz46cmPKyV0BA==","signature_status":"signed_v1","signed_at":"2026-07-05T09:47:35.539207Z","signed_message":"canonical_sha256_bytes"},"source_id":"2410.14612","source_kind":"arxiv","source_version":2}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:d495f60c8f7ea8fce3b72d5fdc6f45f73f80193c9ebe4e9f760a6cce1a4f6b36","sha256:5af8ad135b3a24f3138e86e892462ec3393c333283ef0d8065e48c112a6b946b"],"state_sha256":"b44783df0bec09f351d10988ee3d58e8d27ae2e1d0bb62f1820408b4c2db03fc"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"Gz186WkPr71MxC+QgDu7VnofR8GTLZ7vvhlyvZElbSaxF0idD7YdHNWqq8wRJi6fyHIZMB0CrgTDc4ED+7ObCQ==","signed_message":"bundle_sha256_bytes","signed_at":"2026-08-04T08:55:04.560125Z","bundle_sha256":"691e8f724473ef064fd46c8e5aaeecbe61edee9022d77847d6441a21658f6eaf"}}