{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2017:YIYSSQJK5R4NDMMOHIKHJE3LIW","short_pith_number":"pith:YIYSSQJK","canonical_record":{"source":{"id":"1703.02442","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cs.CV","submitted_at":"2017-03-03T19:03:08Z","cross_cats_sorted":[],"title_canon_sha256":"1557c8f5551f652aa20eace8a90300bfc9c9b0ab1d37c0d2f1b200b05fa7b188","abstract_canon_sha256":"176277a555f87ce2d7f5632ae1cf1c39d94835fa9a22262f3b286be3c52660b0"},"schema_version":"1.0"},"canonical_sha256":"c23129412aec78d1b18e3a1474936b45bc87eb8742bad8fe05df3f5ec2dc86bb","source":{"kind":"arxiv","id":"1703.02442","version":2},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1703.02442","created_at":"2026-07-05T01:07:23Z"},{"alias_kind":"arxiv_version","alias_value":"1703.02442v2","created_at":"2026-07-05T01:07:23Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1703.02442","created_at":"2026-07-05T01:07:23Z"},{"alias_kind":"pith_short_12","alias_value":"YIYSSQJK5R4N","created_at":"2026-07-05T01:07:23Z"},{"alias_kind":"pith_short_16","alias_value":"YIYSSQJK5R4NDMMO","created_at":"2026-07-05T01:07:23Z"},{"alias_kind":"pith_short_8","alias_value":"YIYSSQJK","created_at":"2026-07-05T01:07:23Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2017:YIYSSQJK5R4NDMMOHIKHJE3LIW","target":"record","payload":{"canonical_record":{"source":{"id":"1703.02442","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cs.CV","submitted_at":"2017-03-03T19:03:08Z","cross_cats_sorted":[],"title_canon_sha256":"1557c8f5551f652aa20eace8a90300bfc9c9b0ab1d37c0d2f1b200b05fa7b188","abstract_canon_sha256":"176277a555f87ce2d7f5632ae1cf1c39d94835fa9a22262f3b286be3c52660b0"},"schema_version":"1.0"},"canonical_sha256":"c23129412aec78d1b18e3a1474936b45bc87eb8742bad8fe05df3f5ec2dc86bb","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T01:07:23.711324Z","signature_b64":"QjuQnPBA6l2fHCoIEK277Gj8CZQPj+stCLesK+3G6DTgH4aE6dbp5XA8OYtoBs1A6Csg4FlcYmFHngIsoC/1CQ==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"c23129412aec78d1b18e3a1474936b45bc87eb8742bad8fe05df3f5ec2dc86bb","last_reissued_at":"2026-07-05T01:07:23.710878Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T01:07:23.710878Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1703.02442","source_version":2,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T01:07:23Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"fsw9kxAwnoBE147fEt+c5GW2mH8E6qLonlmihZdnZMdAVUEatZNPgkSg9PXgzNV562pxrijPNX/+XmZqn30SBA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-16T00:40:23.381948Z"},"content_sha256":"1c386978937b20be9205ad4cbb376cb108e0daa86daa3be1e988594089483fe1","schema_version":"1.0","event_id":"sha256:1c386978937b20be9205ad4cbb376cb108e0daa86daa3be1e988594089483fe1"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2017:YIYSSQJK5R4NDMMOHIKHJE3LIW","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Detecting Cancer Metastases on Gigapixel Pathology Images","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"cs.CV","authors_text":"Aleksei Timofeev, Aleksey Boyko, George E. Dahl, Greg S. Corrado, Jason D. Hipp, Krishna Gadepalli, Lily Peng, Martin C. Stumpe, Mohammad Norouzi, Philip Q. Nelson, Subhashini Venugopalan, Timo Kohlberger, Yun Liu","submitted_at":"2017-03-03T19:03:08Z","abstract_excerpt":"Each year, the treatment decisions for more than 230,000 breast cancer patients in the U.S. hinge on whether the cancer has metastasized away from the breast. Metastasis detection is currently performed by pathologists reviewing large expanses of biological tissues. This process is labor intensive and error-prone. We present a framework to automatically detect and localize tumors as small as 100 x 100 pixels in gigapixel microscopy images sized 100,000 x 100,000 pixels. Our method leverages a convolutional neural network (CNN) architecture and obtains state-of-the-art results on the Camelyon16"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1703.02442","kind":"arxiv","version":2},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/1703.02442/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T01:07:23Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"7Je1NVtqWo5BEquCHjFOCLg5lR28TrhZh62pDLCcrdih+FRZ5lYGG7FkhHy6sGuXJS3wdwg73aVjipW0Bn82AA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-16T00:40:23.382823Z"},"content_sha256":"ca05be61c32416e2570b981c8e1b1c50cf06d058a02ae48259e92464c34c0388","schema_version":"1.0","event_id":"sha256:ca05be61c32416e2570b981c8e1b1c50cf06d058a02ae48259e92464c34c0388"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/YIYSSQJK5R4NDMMOHIKHJE3LIW/bundle.json","state_url":"https://pith.science/pith/YIYSSQJK5R4NDMMOHIKHJE3LIW/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/YIYSSQJK5R4NDMMOHIKHJE3LIW/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-08-16T00:40:23Z","links":{"resolver":"https://pith.science/pith/YIYSSQJK5R4NDMMOHIKHJE3LIW","bundle":"https://pith.science/pith/YIYSSQJK5R4NDMMOHIKHJE3LIW/bundle.json","state":"https://pith.science/pith/YIYSSQJK5R4NDMMOHIKHJE3LIW/state.json","well_known_bundle":"https://pith.science/.well-known/pith/YIYSSQJK5R4NDMMOHIKHJE3LIW/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2017:YIYSSQJK5R4NDMMOHIKHJE3LIW","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"176277a555f87ce2d7f5632ae1cf1c39d94835fa9a22262f3b286be3c52660b0","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cs.CV","submitted_at":"2017-03-03T19:03:08Z","title_canon_sha256":"1557c8f5551f652aa20eace8a90300bfc9c9b0ab1d37c0d2f1b200b05fa7b188"},"schema_version":"1.0","source":{"id":"1703.02442","kind":"arxiv","version":2}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1703.02442","created_at":"2026-07-05T01:07:23Z"},{"alias_kind":"arxiv_version","alias_value":"1703.02442v2","created_at":"2026-07-05T01:07:23Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1703.02442","created_at":"2026-07-05T01:07:23Z"},{"alias_kind":"pith_short_12","alias_value":"YIYSSQJK5R4N","created_at":"2026-07-05T01:07:23Z"},{"alias_kind":"pith_short_16","alias_value":"YIYSSQJK5R4NDMMO","created_at":"2026-07-05T01:07:23Z"},{"alias_kind":"pith_short_8","alias_value":"YIYSSQJK","created_at":"2026-07-05T01:07:23Z"}],"graph_snapshots":[{"event_id":"sha256:ca05be61c32416e2570b981c8e1b1c50cf06d058a02ae48259e92464c34c0388","target":"graph","created_at":"2026-07-05T01:07:23Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/1703.02442/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Each year, the treatment decisions for more than 230,000 breast cancer patients in the U.S. hinge on whether the cancer has metastasized away from the breast. Metastasis detection is currently performed by pathologists reviewing large expanses of biological tissues. This process is labor intensive and error-prone. We present a framework to automatically detect and localize tumors as small as 100 x 100 pixels in gigapixel microscopy images sized 100,000 x 100,000 pixels. Our method leverages a convolutional neural network (CNN) architecture and obtains state-of-the-art results on the Camelyon16","authors_text":"Aleksei Timofeev, Aleksey Boyko, George E. Dahl, Greg S. Corrado, Jason D. Hipp, Krishna Gadepalli, Lily Peng, Martin C. Stumpe, Mohammad Norouzi, Philip Q. Nelson, Subhashini Venugopalan, Timo Kohlberger, Yun Liu","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cs.CV","submitted_at":"2017-03-03T19:03:08Z","title":"Detecting Cancer Metastases on Gigapixel Pathology Images"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1703.02442","kind":"arxiv","version":2},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:1c386978937b20be9205ad4cbb376cb108e0daa86daa3be1e988594089483fe1","target":"record","created_at":"2026-07-05T01:07:23Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"176277a555f87ce2d7f5632ae1cf1c39d94835fa9a22262f3b286be3c52660b0","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cs.CV","submitted_at":"2017-03-03T19:03:08Z","title_canon_sha256":"1557c8f5551f652aa20eace8a90300bfc9c9b0ab1d37c0d2f1b200b05fa7b188"},"schema_version":"1.0","source":{"id":"1703.02442","kind":"arxiv","version":2}},"canonical_sha256":"c23129412aec78d1b18e3a1474936b45bc87eb8742bad8fe05df3f5ec2dc86bb","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"c23129412aec78d1b18e3a1474936b45bc87eb8742bad8fe05df3f5ec2dc86bb","first_computed_at":"2026-07-05T01:07:23.710878Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T01:07:23.710878Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"QjuQnPBA6l2fHCoIEK277Gj8CZQPj+stCLesK+3G6DTgH4aE6dbp5XA8OYtoBs1A6Csg4FlcYmFHngIsoC/1CQ==","signature_status":"signed_v1","signed_at":"2026-07-05T01:07:23.711324Z","signed_message":"canonical_sha256_bytes"},"source_id":"1703.02442","source_kind":"arxiv","source_version":2}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:1c386978937b20be9205ad4cbb376cb108e0daa86daa3be1e988594089483fe1","sha256:ca05be61c32416e2570b981c8e1b1c50cf06d058a02ae48259e92464c34c0388"],"state_sha256":"4462056367cd1913ab60377833a1c7bbe140620cd2e23194ce5b0c6884e9d52d"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"4nbMTxB751ljtfPS+zIlz5LosmMNj2moClULrEwcZte6MkZLBk+mbOV/uzjPjZiWozgIkBAzE+PB8rEpGOQyAg==","signed_message":"bundle_sha256_bytes","signed_at":"2026-08-16T00:40:23.388250Z","bundle_sha256":"19bfa62b9c8be3d323b1bf2f917c48653d2f604275c44d811bc3f3992122ccd4"}}