{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2022:YN3G6QKGJM52ABHW3MJM3UXDDX","short_pith_number":"pith:YN3G6QKG","canonical_record":{"source":{"id":"2210.06664","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by-nc-sa/4.0/","primary_cat":"eess.IV","submitted_at":"2022-10-13T01:51:29Z","cross_cats_sorted":["cs.AI","cs.CV"],"title_canon_sha256":"5c5f4c9b4530f83b1a4557cbb5d79dde7258b129ba96b111162a2467250997e8","abstract_canon_sha256":"69d53fddc9226e26ae99e5e6da6d28d93e7816333f196f4a42f924c751cdb173"},"schema_version":"1.0"},"canonical_sha256":"c3766f41464b3ba004f6db12cdd2e31df5421336a329dc094fb697100ad06b76","source":{"kind":"arxiv","id":"2210.06664","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2210.06664","created_at":"2026-07-05T05:06:18Z"},{"alias_kind":"arxiv_version","alias_value":"2210.06664v1","created_at":"2026-07-05T05:06:18Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2210.06664","created_at":"2026-07-05T05:06:18Z"},{"alias_kind":"pith_short_12","alias_value":"YN3G6QKGJM52","created_at":"2026-07-05T05:06:18Z"},{"alias_kind":"pith_short_16","alias_value":"YN3G6QKGJM52ABHW","created_at":"2026-07-05T05:06:18Z"},{"alias_kind":"pith_short_8","alias_value":"YN3G6QKG","created_at":"2026-07-05T05:06:18Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2022:YN3G6QKGJM52ABHW3MJM3UXDDX","target":"record","payload":{"canonical_record":{"source":{"id":"2210.06664","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by-nc-sa/4.0/","primary_cat":"eess.IV","submitted_at":"2022-10-13T01:51:29Z","cross_cats_sorted":["cs.AI","cs.CV"],"title_canon_sha256":"5c5f4c9b4530f83b1a4557cbb5d79dde7258b129ba96b111162a2467250997e8","abstract_canon_sha256":"69d53fddc9226e26ae99e5e6da6d28d93e7816333f196f4a42f924c751cdb173"},"schema_version":"1.0"},"canonical_sha256":"c3766f41464b3ba004f6db12cdd2e31df5421336a329dc094fb697100ad06b76","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-05T05:06:18.471900Z","signature_b64":"3b5M94JMqOAECMkxVjh8BIVtIYcDZVY5F34nZYMsTaz03JYlmmHAmGG5kNYAOPbWHIghWUUo6JUggEMmXWhGDA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"c3766f41464b3ba004f6db12cdd2e31df5421336a329dc094fb697100ad06b76","last_reissued_at":"2026-07-05T05:06:18.471451Z","signature_status":"signed_v1","first_computed_at":"2026-07-05T05:06:18.471451Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2210.06664","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T05:06:18Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"/HlOQcABSapA0tT75FILCaK9Cpdv6vFqVnNBFxNv+T5mZIiDeHmgABuu5tVfxvtS8OFmuLBZn87OPK2N6lm2Aw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-07-18T20:01:47.849930Z"},"content_sha256":"3c84d4398f9742aee2da5e1093d88c8c346e3ae748ba43cafdd67ec79d59cc0d","schema_version":"1.0","event_id":"sha256:3c84d4398f9742aee2da5e1093d88c8c346e3ae748ba43cafdd67ec79d59cc0d"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2022:YN3G6QKGJM52ABHW3MJM3UXDDX","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Are Macula or Optic Nerve Head Structures better at Diagnosing Glaucoma? An Answer using AI and Wide-Field Optical Coherence Tomography","license":"http://creativecommons.org/licenses/by-nc-sa/4.0/","headline":"","cross_cats":["cs.AI","cs.CV"],"primary_cat":"eess.IV","authors_text":"Alexandre Thiery, Charis Y.N. Chiang, Fabian Braeu, Jacqueline Chua, Leopold Schmetterer, Martin Buist, Micha\\\"el J.A. Girard, Royston K.Y. Tan, Thanadet Chuangsuwanich","submitted_at":"2022-10-13T01:51:29Z","abstract_excerpt":"Purpose: (1) To develop a deep learning algorithm to automatically segment structures of the optic nerve head (ONH) and macula in 3D wide-field optical coherence tomography (OCT) scans; (2) To assess whether 3D macula or ONH structures (or the combination of both) provide the best diagnostic power for glaucoma. Methods: A cross-sectional comparative study was performed which included wide-field swept-source OCT scans from 319 glaucoma subjects and 298 non-glaucoma subjects. All scans were compensated to improve deep-tissue visibility. We developed a deep learning algorithm to automatically lab"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2210.06664","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2210.06664/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-05T05:06:18Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"/fKbWl5rwDcxTPvZ9ZRkv0YfS28qxhH68vYIOFZ4zayKyTwpVptOm+tEJJxd4T1KU8goL6gZZCr1aDwhY4LyBQ==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-07-18T20:01:47.850313Z"},"content_sha256":"8aea36649a839fa352eb45bf736e1b71d0cc355e22be9a097b56a94105fbd70c","schema_version":"1.0","event_id":"sha256:8aea36649a839fa352eb45bf736e1b71d0cc355e22be9a097b56a94105fbd70c"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/YN3G6QKGJM52ABHW3MJM3UXDDX/bundle.json","state_url":"https://pith.science/pith/YN3G6QKGJM52ABHW3MJM3UXDDX/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/YN3G6QKGJM52ABHW3MJM3UXDDX/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-07-18T20:01:47Z","links":{"resolver":"https://pith.science/pith/YN3G6QKGJM52ABHW3MJM3UXDDX","bundle":"https://pith.science/pith/YN3G6QKGJM52ABHW3MJM3UXDDX/bundle.json","state":"https://pith.science/pith/YN3G6QKGJM52ABHW3MJM3UXDDX/state.json","well_known_bundle":"https://pith.science/.well-known/pith/YN3G6QKGJM52ABHW3MJM3UXDDX/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2022:YN3G6QKGJM52ABHW3MJM3UXDDX","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"69d53fddc9226e26ae99e5e6da6d28d93e7816333f196f4a42f924c751cdb173","cross_cats_sorted":["cs.AI","cs.CV"],"license":"http://creativecommons.org/licenses/by-nc-sa/4.0/","primary_cat":"eess.IV","submitted_at":"2022-10-13T01:51:29Z","title_canon_sha256":"5c5f4c9b4530f83b1a4557cbb5d79dde7258b129ba96b111162a2467250997e8"},"schema_version":"1.0","source":{"id":"2210.06664","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2210.06664","created_at":"2026-07-05T05:06:18Z"},{"alias_kind":"arxiv_version","alias_value":"2210.06664v1","created_at":"2026-07-05T05:06:18Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2210.06664","created_at":"2026-07-05T05:06:18Z"},{"alias_kind":"pith_short_12","alias_value":"YN3G6QKGJM52","created_at":"2026-07-05T05:06:18Z"},{"alias_kind":"pith_short_16","alias_value":"YN3G6QKGJM52ABHW","created_at":"2026-07-05T05:06:18Z"},{"alias_kind":"pith_short_8","alias_value":"YN3G6QKG","created_at":"2026-07-05T05:06:18Z"}],"graph_snapshots":[{"event_id":"sha256:8aea36649a839fa352eb45bf736e1b71d0cc355e22be9a097b56a94105fbd70c","target":"graph","created_at":"2026-07-05T05:06:18Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2210.06664/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Purpose: (1) To develop a deep learning algorithm to automatically segment structures of the optic nerve head (ONH) and macula in 3D wide-field optical coherence tomography (OCT) scans; (2) To assess whether 3D macula or ONH structures (or the combination of both) provide the best diagnostic power for glaucoma. Methods: A cross-sectional comparative study was performed which included wide-field swept-source OCT scans from 319 glaucoma subjects and 298 non-glaucoma subjects. All scans were compensated to improve deep-tissue visibility. We developed a deep learning algorithm to automatically lab","authors_text":"Alexandre Thiery, Charis Y.N. Chiang, Fabian Braeu, Jacqueline Chua, Leopold Schmetterer, Martin Buist, Micha\\\"el J.A. Girard, Royston K.Y. Tan, Thanadet Chuangsuwanich","cross_cats":["cs.AI","cs.CV"],"headline":"","license":"http://creativecommons.org/licenses/by-nc-sa/4.0/","primary_cat":"eess.IV","submitted_at":"2022-10-13T01:51:29Z","title":"Are Macula or Optic Nerve Head Structures better at Diagnosing Glaucoma? An Answer using AI and Wide-Field Optical Coherence Tomography"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2210.06664","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:3c84d4398f9742aee2da5e1093d88c8c346e3ae748ba43cafdd67ec79d59cc0d","target":"record","created_at":"2026-07-05T05:06:18Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"69d53fddc9226e26ae99e5e6da6d28d93e7816333f196f4a42f924c751cdb173","cross_cats_sorted":["cs.AI","cs.CV"],"license":"http://creativecommons.org/licenses/by-nc-sa/4.0/","primary_cat":"eess.IV","submitted_at":"2022-10-13T01:51:29Z","title_canon_sha256":"5c5f4c9b4530f83b1a4557cbb5d79dde7258b129ba96b111162a2467250997e8"},"schema_version":"1.0","source":{"id":"2210.06664","kind":"arxiv","version":1}},"canonical_sha256":"c3766f41464b3ba004f6db12cdd2e31df5421336a329dc094fb697100ad06b76","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"c3766f41464b3ba004f6db12cdd2e31df5421336a329dc094fb697100ad06b76","first_computed_at":"2026-07-05T05:06:18.471451Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-05T05:06:18.471451Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"3b5M94JMqOAECMkxVjh8BIVtIYcDZVY5F34nZYMsTaz03JYlmmHAmGG5kNYAOPbWHIghWUUo6JUggEMmXWhGDA==","signature_status":"signed_v1","signed_at":"2026-07-05T05:06:18.471900Z","signed_message":"canonical_sha256_bytes"},"source_id":"2210.06664","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:3c84d4398f9742aee2da5e1093d88c8c346e3ae748ba43cafdd67ec79d59cc0d","sha256:8aea36649a839fa352eb45bf736e1b71d0cc355e22be9a097b56a94105fbd70c"],"state_sha256":"cd7f36bcfb116907037db97ad7351142fa837733038be04837d8400b5b6bc120"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"aPgKFhIiW1eR/Ypfsgrid7YZuIGC5/S0fu4paCLbGI0ESPFboTxRXaIcsi1iv+d/gvMK8Gkv/697z+H3YgFoDA==","signed_message":"bundle_sha256_bytes","signed_at":"2026-07-18T20:01:47.852814Z","bundle_sha256":"5c10131f6452196e0fe508d518f4c704fb77dbcb56b2384aeb6d1287f4b01aee"}}