{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2008:ZJWOPICDLGBH5ICRKNWFDKCAPU","short_pith_number":"pith:ZJWOPICD","canonical_record":{"source":{"id":"0810.4550","kind":"arxiv","version":3},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2008-10-24T20:57:56Z","cross_cats_sorted":["q-bio.CB"],"title_canon_sha256":"d34c2a1392897651bae0decdc63a497667ae4078a3443b51b9cd6b3240875ba5","abstract_canon_sha256":"721f7d565e81cc6776810cdf38fa443440d300b28621a04a910a2e866a44e008"},"schema_version":"1.0"},"canonical_sha256":"ca6ce7a04359827ea051536c51a8407d0dec73117ed865341623b3c0eedcecfa","source":{"kind":"arxiv","id":"0810.4550","version":3},"source_aliases":[{"alias_kind":"arxiv","alias_value":"0810.4550","created_at":"2026-07-04T15:42:05Z"},{"alias_kind":"arxiv_version","alias_value":"0810.4550v3","created_at":"2026-07-04T15:42:05Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.0810.4550","created_at":"2026-07-04T15:42:05Z"},{"alias_kind":"pith_short_12","alias_value":"ZJWOPICDLGBH","created_at":"2026-07-04T15:42:05Z"},{"alias_kind":"pith_short_16","alias_value":"ZJWOPICDLGBH5ICR","created_at":"2026-07-04T15:42:05Z"},{"alias_kind":"pith_short_8","alias_value":"ZJWOPICD","created_at":"2026-07-04T15:42:05Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2008:ZJWOPICDLGBH5ICRKNWFDKCAPU","target":"record","payload":{"canonical_record":{"source":{"id":"0810.4550","kind":"arxiv","version":3},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2008-10-24T20:57:56Z","cross_cats_sorted":["q-bio.CB"],"title_canon_sha256":"d34c2a1392897651bae0decdc63a497667ae4078a3443b51b9cd6b3240875ba5","abstract_canon_sha256":"721f7d565e81cc6776810cdf38fa443440d300b28621a04a910a2e866a44e008"},"schema_version":"1.0"},"canonical_sha256":"ca6ce7a04359827ea051536c51a8407d0dec73117ed865341623b3c0eedcecfa","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-07-04T15:42:05.384600Z","signature_b64":"5dV6KYn1qDlXZU4e7t7Omg3zfpKoKLES/TYDqSScEMKQU/pSBug08jzoUjtjy79DqZZ7DFDa4RzNuW4UCEMHDg==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"ca6ce7a04359827ea051536c51a8407d0dec73117ed865341623b3c0eedcecfa","last_reissued_at":"2026-07-04T15:42:05.384190Z","signature_status":"signed_v1","first_computed_at":"2026-07-04T15:42:05.384190Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"0810.4550","source_version":3,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-04T15:42:05Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"od17088O5+wqZswf2zSpo/xm2JDGf95Aj6KJpZVjoV1T+QRe3wZz69DxNb7tub7btYpIFFX7BMLgrpZAI6oPDA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-03T19:15:24.227530Z"},"content_sha256":"0c2e90e620020680c04790c516ec401746eff273698b469cc92445d7e2754044","schema_version":"1.0","event_id":"sha256:0c2e90e620020680c04790c516ec401746eff273698b469cc92445d7e2754044"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2008:ZJWOPICDLGBH5ICRKNWFDKCAPU","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Probing embryonic tissue mechanics with laser hole-drilling","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["q-bio.CB"],"primary_cat":"physics.bio-ph","authors_text":"Holley E. Lynch, M. Shane Hutson, Peter C. Scully, Xiaoyan Ma","submitted_at":"2008-10-24T20:57:56Z","abstract_excerpt":"We use laser hole-drilling to assess the mechanics of an embryonic epithelium during development - in vivo and with subcellular resolution. We ablate a subcellular cylindrical hole clean through the epithelium, and track the subsequent recoil of adjacent cells (on ms time scales). We investigate dorsal closure in the fruit fly with emphasis on apical constriction of amnioserosa cells. The mechanical behavior of this epithelium falls between that of a continuous sheet and a 2D cellular foam (a network of tensile interfaces). Tensile stress is carried both by cell-cell interfaces and by the cell"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"0810.4550","kind":"arxiv","version":3},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/0810.4550/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-07-04T15:42:05Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"vJYvnq2SA2ts/+bdUsijrBYDZdJnfPjoH80GdUk72E2jvdv4jZuBCdbF6CIEy9cfIbovZXoUNJYtrwBrDvZ4BA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-08-03T19:15:24.228574Z"},"content_sha256":"51a7a5f6cbb27746a15af6def60bd0fca894a9d2b9a415f2c63a1234860d0d97","schema_version":"1.0","event_id":"sha256:51a7a5f6cbb27746a15af6def60bd0fca894a9d2b9a415f2c63a1234860d0d97"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/ZJWOPICDLGBH5ICRKNWFDKCAPU/bundle.json","state_url":"https://pith.science/pith/ZJWOPICDLGBH5ICRKNWFDKCAPU/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/ZJWOPICDLGBH5ICRKNWFDKCAPU/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-08-03T19:15:24Z","links":{"resolver":"https://pith.science/pith/ZJWOPICDLGBH5ICRKNWFDKCAPU","bundle":"https://pith.science/pith/ZJWOPICDLGBH5ICRKNWFDKCAPU/bundle.json","state":"https://pith.science/pith/ZJWOPICDLGBH5ICRKNWFDKCAPU/state.json","well_known_bundle":"https://pith.science/.well-known/pith/ZJWOPICDLGBH5ICRKNWFDKCAPU/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2008:ZJWOPICDLGBH5ICRKNWFDKCAPU","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"721f7d565e81cc6776810cdf38fa443440d300b28621a04a910a2e866a44e008","cross_cats_sorted":["q-bio.CB"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2008-10-24T20:57:56Z","title_canon_sha256":"d34c2a1392897651bae0decdc63a497667ae4078a3443b51b9cd6b3240875ba5"},"schema_version":"1.0","source":{"id":"0810.4550","kind":"arxiv","version":3}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"0810.4550","created_at":"2026-07-04T15:42:05Z"},{"alias_kind":"arxiv_version","alias_value":"0810.4550v3","created_at":"2026-07-04T15:42:05Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.0810.4550","created_at":"2026-07-04T15:42:05Z"},{"alias_kind":"pith_short_12","alias_value":"ZJWOPICDLGBH","created_at":"2026-07-04T15:42:05Z"},{"alias_kind":"pith_short_16","alias_value":"ZJWOPICDLGBH5ICR","created_at":"2026-07-04T15:42:05Z"},{"alias_kind":"pith_short_8","alias_value":"ZJWOPICD","created_at":"2026-07-04T15:42:05Z"}],"graph_snapshots":[{"event_id":"sha256:51a7a5f6cbb27746a15af6def60bd0fca894a9d2b9a415f2c63a1234860d0d97","target":"graph","created_at":"2026-07-04T15:42:05Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/0810.4550/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"We use laser hole-drilling to assess the mechanics of an embryonic epithelium during development - in vivo and with subcellular resolution. We ablate a subcellular cylindrical hole clean through the epithelium, and track the subsequent recoil of adjacent cells (on ms time scales). We investigate dorsal closure in the fruit fly with emphasis on apical constriction of amnioserosa cells. The mechanical behavior of this epithelium falls between that of a continuous sheet and a 2D cellular foam (a network of tensile interfaces). Tensile stress is carried both by cell-cell interfaces and by the cell","authors_text":"Holley E. Lynch, M. Shane Hutson, Peter C. Scully, Xiaoyan Ma","cross_cats":["q-bio.CB"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2008-10-24T20:57:56Z","title":"Probing embryonic tissue mechanics with laser hole-drilling"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"0810.4550","kind":"arxiv","version":3},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:0c2e90e620020680c04790c516ec401746eff273698b469cc92445d7e2754044","target":"record","created_at":"2026-07-04T15:42:05Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"721f7d565e81cc6776810cdf38fa443440d300b28621a04a910a2e866a44e008","cross_cats_sorted":["q-bio.CB"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2008-10-24T20:57:56Z","title_canon_sha256":"d34c2a1392897651bae0decdc63a497667ae4078a3443b51b9cd6b3240875ba5"},"schema_version":"1.0","source":{"id":"0810.4550","kind":"arxiv","version":3}},"canonical_sha256":"ca6ce7a04359827ea051536c51a8407d0dec73117ed865341623b3c0eedcecfa","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"ca6ce7a04359827ea051536c51a8407d0dec73117ed865341623b3c0eedcecfa","first_computed_at":"2026-07-04T15:42:05.384190Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-07-04T15:42:05.384190Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"5dV6KYn1qDlXZU4e7t7Omg3zfpKoKLES/TYDqSScEMKQU/pSBug08jzoUjtjy79DqZZ7DFDa4RzNuW4UCEMHDg==","signature_status":"signed_v1","signed_at":"2026-07-04T15:42:05.384600Z","signed_message":"canonical_sha256_bytes"},"source_id":"0810.4550","source_kind":"arxiv","source_version":3}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:0c2e90e620020680c04790c516ec401746eff273698b469cc92445d7e2754044","sha256:51a7a5f6cbb27746a15af6def60bd0fca894a9d2b9a415f2c63a1234860d0d97"],"state_sha256":"82ef5be2428da90b61e0b4da4401eaeb2252fd4ddbdb9850f2eb2bfc99cd2a28"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"kBFf0+aP3BBoLD9Arh07qaRgAIiykCUxeyWNVmN6WqQJmnYi3FGXQ80+kjx2FtCWk08xCy94W7YTFkyub6c5Bg==","signed_message":"bundle_sha256_bytes","signed_at":"2026-08-03T19:15:24.238157Z","bundle_sha256":"14037d1ef57df3ca6b2f387f0c853194f541a0386b03a157ea68bd2b9f3869c5"}}