{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2016:ZRR3ODG73WRHX24HIV2JUTTFVG","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"2a5fad2d79a11af77821eccb8cab2a8041fdf113ca30dc61f9db448fde00caec","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cond-mat.soft","submitted_at":"2016-08-03T15:28:39Z","title_canon_sha256":"6b4a8de85287aac67e4cc1c16126751cfe0907a6020a81850810de5c573d508e"},"schema_version":"1.0","source":{"id":"1608.01222","kind":"arxiv","version":2}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1608.01222","created_at":"2026-05-18T00:47:26Z"},{"alias_kind":"arxiv_version","alias_value":"1608.01222v2","created_at":"2026-05-18T00:47:26Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1608.01222","created_at":"2026-05-18T00:47:26Z"},{"alias_kind":"pith_short_12","alias_value":"ZRR3ODG73WRH","created_at":"2026-05-18T12:30:55Z"},{"alias_kind":"pith_short_16","alias_value":"ZRR3ODG73WRHX24H","created_at":"2026-05-18T12:30:55Z"},{"alias_kind":"pith_short_8","alias_value":"ZRR3ODG7","created_at":"2026-05-18T12:30:55Z"}],"graph_snapshots":[{"event_id":"sha256:349e8ce5c16b30df7b169f34cfa5a65ef6afd4499dae48f066acbd3170cfb975","target":"graph","created_at":"2026-05-18T00:47:26Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Multivalent particles have the ability to form multiple bonds to a substrate. Hence, a multivalent interaction can be strong, even if the individual bonds are weak. However, much more interestingly, multivalency greatly increases the sensitivity of the particle-substrate interaction to external conditions, resulting in an ultra-sensitive and highly non-linear dependence of the binding strength on parameters such as temperature, pH or receptor concentration.\n  In this chapter we focus on super-selectivity: the high sensitivity of the strength of multivalent binding to the number of accessible b","authors_text":"Daan Frenkel, Jure Dobnikar, Tine Curk","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cond-mat.soft","submitted_at":"2016-08-03T15:28:39Z","title":"Design principles for super selectivity using multivalent interactions"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1608.01222","kind":"arxiv","version":2},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:d5859df9aa5850144aa50554b63516a26e8f2e33afdc4589a2bf1a081ad00229","target":"record","created_at":"2026-05-18T00:47:26Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"2a5fad2d79a11af77821eccb8cab2a8041fdf113ca30dc61f9db448fde00caec","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cond-mat.soft","submitted_at":"2016-08-03T15:28:39Z","title_canon_sha256":"6b4a8de85287aac67e4cc1c16126751cfe0907a6020a81850810de5c573d508e"},"schema_version":"1.0","source":{"id":"1608.01222","kind":"arxiv","version":2}},"canonical_sha256":"cc63b70cdfdda27beb8745749a4e65a9953783496cf7ea0322f2196764d34977","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"cc63b70cdfdda27beb8745749a4e65a9953783496cf7ea0322f2196764d34977","first_computed_at":"2026-05-18T00:47:26.923662Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T00:47:26.923662Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"242uZmfVzgGJ+yc/Fmaz99Ye3RBUhYmwG1SfijFw2QEDKO+1XN7DLNyyxiyufPxg7s9Zkz//FjZ5GcPo6RxyDg==","signature_status":"signed_v1","signed_at":"2026-05-18T00:47:26.924193Z","signed_message":"canonical_sha256_bytes"},"source_id":"1608.01222","source_kind":"arxiv","source_version":2}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:d5859df9aa5850144aa50554b63516a26e8f2e33afdc4589a2bf1a081ad00229","sha256:349e8ce5c16b30df7b169f34cfa5a65ef6afd4499dae48f066acbd3170cfb975"],"state_sha256":"ddc7050ffdd58e1c540ebbf15fb94050dd67668ebcd01960cbd90d1c3855d20c"}