{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2016:ZWS34RMJRG4QGONIB7JFVIXUK4","short_pith_number":"pith:ZWS34RMJ","canonical_record":{"source":{"id":"1612.08814","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2016-12-28T06:59:15Z","cross_cats_sorted":["cond-mat.mes-hall","q-bio.BM"],"title_canon_sha256":"1108153b2427783ca76a0965aa9b9ae661a541b4f9448b25a6d3535f7690fc85","abstract_canon_sha256":"551079130fdd85466069286b4dc8cc6d4b99a0a8830012f97e65d50c7b87c259"},"schema_version":"1.0"},"canonical_sha256":"cda5be458989b90339a80fd25aa2f45700c6ac14c083b2bf6146af5fb5c2c81a","source":{"kind":"arxiv","id":"1612.08814","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1612.08814","created_at":"2026-05-18T00:53:47Z"},{"alias_kind":"arxiv_version","alias_value":"1612.08814v1","created_at":"2026-05-18T00:53:47Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1612.08814","created_at":"2026-05-18T00:53:47Z"},{"alias_kind":"pith_short_12","alias_value":"ZWS34RMJRG4Q","created_at":"2026-05-18T12:30:55Z"},{"alias_kind":"pith_short_16","alias_value":"ZWS34RMJRG4QGONI","created_at":"2026-05-18T12:30:55Z"},{"alias_kind":"pith_short_8","alias_value":"ZWS34RMJ","created_at":"2026-05-18T12:30:55Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2016:ZWS34RMJRG4QGONIB7JFVIXUK4","target":"record","payload":{"canonical_record":{"source":{"id":"1612.08814","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2016-12-28T06:59:15Z","cross_cats_sorted":["cond-mat.mes-hall","q-bio.BM"],"title_canon_sha256":"1108153b2427783ca76a0965aa9b9ae661a541b4f9448b25a6d3535f7690fc85","abstract_canon_sha256":"551079130fdd85466069286b4dc8cc6d4b99a0a8830012f97e65d50c7b87c259"},"schema_version":"1.0"},"canonical_sha256":"cda5be458989b90339a80fd25aa2f45700c6ac14c083b2bf6146af5fb5c2c81a","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T00:53:47.105934Z","signature_b64":"mJrrxlmDoVVcmowDNEBJjlLedSgTxmM2zBDcswiEOv9ud/TMW6bsgVSFiCBYXirFV5ihpTjdhr7bdrjbeFTNCA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"cda5be458989b90339a80fd25aa2f45700c6ac14c083b2bf6146af5fb5c2c81a","last_reissued_at":"2026-05-18T00:53:47.105527Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T00:53:47.105527Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1612.08814","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T00:53:47Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"mbupHPgj0njZ6b5L0YGIFZLxz2Wl6FSOvRs5NuARA6P7Iv0/civ9bHElsS/7DLmDY5Us9wyBOjE4Gmrhb3YeDw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-24T13:27:31.694951Z"},"content_sha256":"f85b33e7c5a73630c2b52a268559318f53dc1d32304f093de1fe8232d0801e9b","schema_version":"1.0","event_id":"sha256:f85b33e7c5a73630c2b52a268559318f53dc1d32304f093de1fe8232d0801e9b"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2016:ZWS34RMJRG4QGONIB7JFVIXUK4","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Protein corona composition of PEGylated nanoparticles correlates strongly with amino acid composition of protein surface","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["cond-mat.mes-hall","q-bio.BM"],"primary_cat":"physics.bio-ph","authors_text":"Friederike Schmid, Giovanni Settanni, Jiajia Zhou, Katharina Landfester, Susanne Sch\\\"ottler, Tongchuan Suo, Volker Mail\\\"ander","submitted_at":"2016-12-28T06:59:15Z","abstract_excerpt":"Extensive molecular dynamics simulations reveal that the interactions between proteins and poly(ethylene glycol)(PEG) can be described in terms of the surface composition of the proteins. PEG molecules accumulate around non-polar residues while avoiding polar ones. A solvent-accessible-surface-area model of protein adsorption on PEGylated nanoparticles accurately fits a large set of data on the composition of the protein corona recently obtained by label-free proteomic mass spectrometry."},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1612.08814","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T00:53:47Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"SmyTBSi3c+NS+Thp7CrTT1VIjIwxEf35KjoTYjgLMNnt82UygCTBhA4pR3NF7Pd9PftBaqDMwHZXvhCW+PtUAg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-24T13:27:31.695519Z"},"content_sha256":"020913230c61bcb6b0008d41362a2b6b7dec53b4c1d5879b289815139fb33423","schema_version":"1.0","event_id":"sha256:020913230c61bcb6b0008d41362a2b6b7dec53b4c1d5879b289815139fb33423"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/ZWS34RMJRG4QGONIB7JFVIXUK4/bundle.json","state_url":"https://pith.science/pith/ZWS34RMJRG4QGONIB7JFVIXUK4/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/ZWS34RMJRG4QGONIB7JFVIXUK4/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-05-24T13:27:31Z","links":{"resolver":"https://pith.science/pith/ZWS34RMJRG4QGONIB7JFVIXUK4","bundle":"https://pith.science/pith/ZWS34RMJRG4QGONIB7JFVIXUK4/bundle.json","state":"https://pith.science/pith/ZWS34RMJRG4QGONIB7JFVIXUK4/state.json","well_known_bundle":"https://pith.science/.well-known/pith/ZWS34RMJRG4QGONIB7JFVIXUK4/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2016:ZWS34RMJRG4QGONIB7JFVIXUK4","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"551079130fdd85466069286b4dc8cc6d4b99a0a8830012f97e65d50c7b87c259","cross_cats_sorted":["cond-mat.mes-hall","q-bio.BM"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2016-12-28T06:59:15Z","title_canon_sha256":"1108153b2427783ca76a0965aa9b9ae661a541b4f9448b25a6d3535f7690fc85"},"schema_version":"1.0","source":{"id":"1612.08814","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1612.08814","created_at":"2026-05-18T00:53:47Z"},{"alias_kind":"arxiv_version","alias_value":"1612.08814v1","created_at":"2026-05-18T00:53:47Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1612.08814","created_at":"2026-05-18T00:53:47Z"},{"alias_kind":"pith_short_12","alias_value":"ZWS34RMJRG4Q","created_at":"2026-05-18T12:30:55Z"},{"alias_kind":"pith_short_16","alias_value":"ZWS34RMJRG4QGONI","created_at":"2026-05-18T12:30:55Z"},{"alias_kind":"pith_short_8","alias_value":"ZWS34RMJ","created_at":"2026-05-18T12:30:55Z"}],"graph_snapshots":[{"event_id":"sha256:020913230c61bcb6b0008d41362a2b6b7dec53b4c1d5879b289815139fb33423","target":"graph","created_at":"2026-05-18T00:53:47Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Extensive molecular dynamics simulations reveal that the interactions between proteins and poly(ethylene glycol)(PEG) can be described in terms of the surface composition of the proteins. PEG molecules accumulate around non-polar residues while avoiding polar ones. A solvent-accessible-surface-area model of protein adsorption on PEGylated nanoparticles accurately fits a large set of data on the composition of the protein corona recently obtained by label-free proteomic mass spectrometry.","authors_text":"Friederike Schmid, Giovanni Settanni, Jiajia Zhou, Katharina Landfester, Susanne Sch\\\"ottler, Tongchuan Suo, Volker Mail\\\"ander","cross_cats":["cond-mat.mes-hall","q-bio.BM"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2016-12-28T06:59:15Z","title":"Protein corona composition of PEGylated nanoparticles correlates strongly with amino acid composition of protein surface"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1612.08814","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:f85b33e7c5a73630c2b52a268559318f53dc1d32304f093de1fe8232d0801e9b","target":"record","created_at":"2026-05-18T00:53:47Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"551079130fdd85466069286b4dc8cc6d4b99a0a8830012f97e65d50c7b87c259","cross_cats_sorted":["cond-mat.mes-hall","q-bio.BM"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2016-12-28T06:59:15Z","title_canon_sha256":"1108153b2427783ca76a0965aa9b9ae661a541b4f9448b25a6d3535f7690fc85"},"schema_version":"1.0","source":{"id":"1612.08814","kind":"arxiv","version":1}},"canonical_sha256":"cda5be458989b90339a80fd25aa2f45700c6ac14c083b2bf6146af5fb5c2c81a","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"cda5be458989b90339a80fd25aa2f45700c6ac14c083b2bf6146af5fb5c2c81a","first_computed_at":"2026-05-18T00:53:47.105527Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T00:53:47.105527Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"mJrrxlmDoVVcmowDNEBJjlLedSgTxmM2zBDcswiEOv9ud/TMW6bsgVSFiCBYXirFV5ihpTjdhr7bdrjbeFTNCA==","signature_status":"signed_v1","signed_at":"2026-05-18T00:53:47.105934Z","signed_message":"canonical_sha256_bytes"},"source_id":"1612.08814","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:f85b33e7c5a73630c2b52a268559318f53dc1d32304f093de1fe8232d0801e9b","sha256:020913230c61bcb6b0008d41362a2b6b7dec53b4c1d5879b289815139fb33423"],"state_sha256":"43d2022574b44c0fe6ef5fff96bf13701ecffc5f2a865e83f42ce89710200312"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"ME6faGO6bFcDW1LM0+SoBab5azCAQH/HtGWdyAEhJu5aBEXhYTZW5QwRg5l79ec5+/lHbkq+4L7qSkt1KJv4BA==","signed_message":"bundle_sha256_bytes","signed_at":"2026-05-24T13:27:31.699008Z","bundle_sha256":"7087a4ac564b95721896fb988c0f1b2a1c08112fec36f28bc8f1ba9fac186bba"}}