SmileyLlama is an LLM transformed via SFT and DPO to generate valid novel drug-like molecules with user-specified properties and optimized 3D conformations for high binding affinity.
https://enamine.net/compound-libraries/ fragment-libraries/essential-library, Accessed: 2024-08-23
1 Pith paper cite this work. Polarity classification is still indexing.
1
Pith paper citing it
fields
physics.chem-ph 1years
2024 1verdicts
UNVERDICTED 1representative citing papers
citing papers explorer
-
SmileyLlama: Modifying Large Language Models for Directed Chemical Space Exploration
SmileyLlama is an LLM transformed via SFT and DPO to generate valid novel drug-like molecules with user-specified properties and optimized 3D conformations for high binding affinity.