A GAMLSS-based parametric method estimates multivariate alert thresholds with confidence regions for time-dose-response data by fitting flexible models and leveraging all observations for extrapolation.
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Estimating effect thresholds and beyond: A flexible framework for multivariate alert detection
A GAMLSS-based parametric method estimates multivariate alert thresholds with confidence regions for time-dose-response data by fitting flexible models and leveraging all observations for extrapolation.