Stochastic simulations of Rho GTPase dynamics demonstrate that intrinsic molecular noise dominates CIL decision variability at low copy numbers, while contact-to-contact geometric variability dominates at high copy numbers.
(20) Here ⟨∆θ⟩CIL and ⟨∆θ⟩free are the ensemble-averaged reorientation angles with and without CIL, respectively (Eq
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Intrinsic stochasticity in cell polarity and contact inhibition of locomotion
Stochastic simulations of Rho GTPase dynamics demonstrate that intrinsic molecular noise dominates CIL decision variability at low copy numbers, while contact-to-contact geometric variability dominates at high copy numbers.