SF-Cluster guides MSA subsampling with frustration patterns to improve alternative protein conformation recovery over sequence-based methods like AF-Cluster on a 48-case benchmark.
An α helix to β barrel domain switch transforms the transcription factor rfah into a translation factor.Cell, 150(2):291–303, 2012
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SF-Cluster: Frustration-Guided MSA Subsampling for Alternative Protein Conformation Recovery
SF-Cluster guides MSA subsampling with frustration patterns to improve alternative protein conformation recovery over sequence-based methods like AF-Cluster on a 48-case benchmark.