High-entropy Boltzmann Machines on protein sequences generate functional artificial enzymes from a viable sequence space more than 15 orders of magnitude larger than low-entropy models while maintaining high success rates in cell-based tests.
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Expanding functional protein sequence space using high entropy generative models
High-entropy Boltzmann Machines on protein sequences generate functional artificial enzymes from a viable sequence space more than 15 orders of magnitude larger than low-entropy models while maintaining high success rates in cell-based tests.