CEP-IP is a new explainable framework that combines dual statistical filtering, generalized additive modeling, and inflection point analysis to identify four biologically distinct cell subpopulations per patient across prostate cancer, brain, and glioblastoma scRNA-seq datasets.
MYC-mediated ribosomal gene expression sensitizes enzalutamide-resistant prostate cancer cells to EP300/CREBBP inhibitors
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CEP-IP: An Explainable Framework for Cell Subpopulation Identification in Single-cell Transcriptomics
CEP-IP is a new explainable framework that combines dual statistical filtering, generalized additive modeling, and inflection point analysis to identify four biologically distinct cell subpopulations per patient across prostate cancer, brain, and glioblastoma scRNA-seq datasets.