Logistic functions replace Hill functions in gene regulatory network ODE models to ensure global smoothness, real-valued trajectories, positive basal production, and stable numerical integration across small and large networks.
Deep model predictive control of gene expression in thousands of single cells
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Logistic Gene Regulatory Networks: Prevention of Expression Shutdown, and Numerical Stability Beyond Hill Function
Logistic functions replace Hill functions in gene regulatory network ODE models to ensure global smoothness, real-valued trajectories, positive basal production, and stable numerical integration across small and large networks.