The paper presents PDFBench, a unified benchmark with 16 metrics and a new post-2025 protein test set, and finds that evaluation choices such as retrieval strategy or supported keywords can dominate model rankings.
Computational design of enzymes for biotechnological applications
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PDFBench: A Benchmark for De novo Protein Design from Function
The paper presents PDFBench, a unified benchmark with 16 metrics and a new post-2025 protein test set, and finds that evaluation choices such as retrieval strategy or supported keywords can dominate model rankings.