SheafStain reinterprets VFM embeddings as sheaf sections within a Schrödinger Bridge, using co-pretrained H&E/IHC backbones to produce spatially and biologically coherent virtual staining evaluated on stitched 1024x1024 outputs for HER2, ER, PR, and Ki-67.
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SheafStain: Sheaf-Theoretic Schr\"odinger Bridge for Spatially and Biologically Coherent Virtual Staining
SheafStain reinterprets VFM embeddings as sheaf sections within a Schrödinger Bridge, using co-pretrained H&E/IHC backbones to produce spatially and biologically coherent virtual staining evaluated on stitched 1024x1024 outputs for HER2, ER, PR, and Ki-67.