Replacing the generic Stable Diffusion VAE with domain-specific MedVAE pretrained on 1.6M medical images improves diffusion-based SR PSNR by 2.91-3.29 dB on knee/brain MRI and chest X-ray, with gains in fine details and VAE quality predicting SR performance (R²=0.67).
Low field, high impact: Democratizing MRI for clinical and research innovation.BJR |Open, 7(1):tzaf022, 2025
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Domain-Specific Latent Representations Improve the Fidelity of Diffusion-Based Medical Image Super-Resolution
Replacing the generic Stable Diffusion VAE with domain-specific MedVAE pretrained on 1.6M medical images improves diffusion-based SR PSNR by 2.91-3.29 dB on knee/brain MRI and chest X-ray, with gains in fine details and VAE quality predicting SR performance (R²=0.67).