SAFE is a new two-layer framework that assesses drug safety in clinical trials by analyzing synergy areas with compelling evidence and controlling FDR across areas, as shown in simulations and real-data case studies.
Efficacy as an important facet of “safety” in clinical trials: how can we do our best for our patients?.Clinical Infectious Diseases2008; 47(Supplement_3): S180–S185
1 Pith paper cite this work. Polarity classification is still indexing.
1
Pith paper citing it
fields
stat.AP 1years
2026 1verdicts
UNVERDICTED 1representative citing papers
citing papers explorer
-
Synergy Area with FDR-controlled Evaluation (SAFE) to robustly assess safety profile in clinical trials
SAFE is a new two-layer framework that assesses drug safety in clinical trials by analyzing synergy areas with compelling evidence and controlling FDR across areas, as shown in simulations and real-data case studies.