Pseudo-value regression extends mediation analysis to time-to-event estimands, giving additive direct and indirect effects on survival probability, RMST, and cumulative incidence scales.
et al.Mediation analysis of the relationship between sex, cardiovascular risk factors and mortality from coronary heart disease: findings from the population-based VHM&PP cohort
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Simplifying Causal Mediation Analysis for Time-to-Event Outcomes using Pseudo-Values
Pseudo-value regression extends mediation analysis to time-to-event estimands, giving additive direct and indirect effects on survival probability, RMST, and cumulative incidence scales.