Multivalent binding maps exactly onto the monomer-dimer problem, so recognition thresholds are necessarily smooth crossovers with log-concave bond distributions, and a single free-energy functional with many-body couplings is illustrated on antibodies, lipoproteins, and T cells.
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A General Theory for Phenotypic Association in Biological Systems
Multivalent binding maps exactly onto the monomer-dimer problem, so recognition thresholds are necessarily smooth crossovers with log-concave bond distributions, and a single free-energy functional with many-body couplings is illustrated on antibodies, lipoproteins, and T cells.