MIST augments MIL projection layers with cross-modal gene-expression prototypes derived from spatial transcriptomics, yielding consistent gains on survival, subtyping, and biomarker tasks across 23 endpoints and 8 aggregators.
Classifica- tion and mutation prediction from non–small cell lung cancer histopathology images using deep learning.Nature medicine, 24(10):1559–1567, 2018
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Bridging the Modality Bottleneck in Pathology MIL through Virtual Molecular Staining
MIST augments MIL projection layers with cross-modal gene-expression prototypes derived from spatial transcriptomics, yielding consistent gains on survival, subtyping, and biomarker tasks across 23 endpoints and 8 aggregators.