StructBioReasoner is a scalable multi-agent system that designs IDP-targeting biologics, with over 50% of 787 candidates for Der f 21 showing better binding free energy than human-designed references.
URL https://www.biorxiv.org/content/10.1101/2024.10.10.615955v1
3 Pith papers cite this work, alongside 359 external citations. Polarity classification is still indexing.
verdicts
UNVERDICTED 3representative citing papers
DeCAF distills all-atom cofolding diffusion models into few-step flow maps, showing improved or matched accuracy on protein-ligand tasks with 5x fewer inference steps.
Emyx, a compact flow matching model with EDM reparametrization, outperforms larger protein generators on enzyme design benchmarks with substantially lower training compute.
citing papers explorer
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Scalable Agentic Reasoning for Designing Biologics Targeting Intrinsically Disordered Proteins
StructBioReasoner is a scalable multi-agent system that designs IDP-targeting biologics, with over 50% of 787 candidates for Der f 21 showing better binding free energy than human-designed references.
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Few-step Cofolding with All-Atom Flow Maps
DeCAF distills all-atom cofolding diffusion models into few-step flow maps, showing improved or matched accuracy on protein-ligand tasks with 5x fewer inference steps.
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Emyx: Fast and efficient all-atom protein generation
Emyx, a compact flow matching model with EDM reparametrization, outperforms larger protein generators on enzyme design benchmarks with substantially lower training compute.