Cryo-atom-probe analysis of a plunge-frozen ferritin solution is feasible, but slow freezing destroys ferritin shells, and high-pressure frozen water shows the needed future route.
However, these are not uncommonly strong, with peaks of only up to a factor of 5 times the set detection rate
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Atom probe tomography of hydrated biomacromolecules: preliminary results
Cryo-atom-probe analysis of a plunge-frozen ferritin solution is feasible, but slow freezing destroys ferritin shells, and high-pressure frozen water shows the needed future route.