IgSeek retrieves structurally similar CDRs from a database of solved antibody structures and uses their sequences to predict the query CDR sequence, outperforming inverse folding baselines in amino-acid recovery.
Hyperparameter Value Description Input noise ratio 0.15 Ratio of the input coordinates with added Gaussian noise
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Fast and Accurate Antibody Sequence Design via Structure Retrieval
IgSeek retrieves structurally similar CDRs from a database of solved antibody structures and uses their sequences to predict the query CDR sequence, outperforming inverse folding baselines in amino-acid recovery.