A frequency-to-amplitude converter architecture lets light-pulse frequency, not just intensity, control gene expression and expands the reachable combinations of multiple genes.
Science 342(6163), 1193–1200 (2013)
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Synthetic frequency-controlled gene circuits unlock expanded cellular states
A frequency-to-amplitude converter architecture lets light-pulse frequency, not just intensity, control gene expression and expands the reachable combinations of multiple genes.