Component-removing blind source separation can collapse causal graph recovery to zero in synthetic calcium traces and dramatically densify connectivity estimates from real v2a-RSN traces, so BSS denoising is not a neutral preprocessing step.
Whole-Brain Activity Maps Reveal Stereotyped, Distributed Networks for Visuomotor Behavior.Neuron2014,81, 1328–1343
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Blind Source Separation Can Distort Behavior and Connectivity Analyses of Calcium Transients
Component-removing blind source separation can collapse causal graph recovery to zero in synthetic calcium traces and dramatically densify connectivity estimates from real v2a-RSN traces, so BSS denoising is not a neutral preprocessing step.