Cohort comparisons cannot produce reliable brain-disease biomarkers due to feature degeneracy; multimodal longitudinal data should instead guide grouping before biomarker definition.
Journal of Consciousness Studies 1(1), 10–16 (1994)
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Pursuit of biomarkers of brain diseases: Beyond cohort comparisons
Cohort comparisons cannot produce reliable brain-disease biomarkers due to feature degeneracy; multimodal longitudinal data should instead guide grouping before biomarker definition.