A 31-node Boolean network of NSCLC drug resistance is reduced to a 9-node core that preserves three steady states, and a fitted BMI1 rule removes an unwanted limit cycle.
Adynamic booleannetworkrevealsthatthebmi1andmalat1axisisassociatedwithdrugresistancebylimitingmir-145-5pinnon-smallcelllungcancer
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Boolean-network simplification and rule fitting to unravel chemotherapy resistance in non-small cell lung cancer
A 31-node Boolean network of NSCLC drug resistance is reduced to a 9-node core that preserves three steady states, and a fitted BMI1 rule removes an unwanted limit cycle.