A STAR-based computational pipeline on bulk and single-cell mouse antibody data identified 67 SPR-validated anti-GFRAL antibodies, with 19 of 40 STAR hits confirmed as binders.
Production of functional chimaeric mouse/human antibody
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Integrating computational detection and experimental validation for rapid GFRAL-specific antibody discovery
A STAR-based computational pipeline on bulk and single-cell mouse antibody data identified 67 SPR-validated anti-GFRAL antibodies, with 19 of 40 STAR hits confirmed as binders.