Activation steering can guide protein language models to generate and optimize sequences with higher predicted thermostability, solubility, or GFP brightness, but only in surrogate-based evaluation.
Protein language model fitness is a matter of preference.bioRxiv, pages 2024–10, 2024
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Steering Protein Language Models
Activation steering can guide protein language models to generate and optimize sequences with higher predicted thermostability, solubility, or GFP brightness, but only in surrogate-based evaluation.