MitoFREQ bounds a mitogenome's population frequency from above as P(TLHG) × (frequency of the profile's rarest SNV within that TLHG), yielding conservative likelihood-ratio evidence weights.
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MitoFREQ: A Novel Approach for Mitogenome Frequency Estimation from Top-level Haplogroups and Single Nucleotide Variants
MitoFREQ bounds a mitogenome's population frequency from above as P(TLHG) × (frequency of the profile's rarest SNV within that TLHG), yielding conservative likelihood-ratio evidence weights.