Across six SARS-CoV-2 variants, tighter ACE2 binding is associated with greater rigidity of the unbound spike RBD and with dynamics that resemble the bound state.
Compact assessment of molecular surface complementarities enhances neural network-aided prediction of key binding residues.Journal of Chemical Information and Modeling , 2025
1 Pith paper cite this work. Polarity classification is still indexing.
1
Pith paper citing it
citation-role summary
background 1
citation-polarity summary
fields
q-bio.BM 1years
2025 1verdicts
CONDITIONAL 1roles
background 1polarities
unclear 1representative citing papers
citing papers explorer
-
Insights into the role of dynamical features in protein complex formation: the case of SARS-CoV-2 spike binding with ACE2
Across six SARS-CoV-2 variants, tighter ACE2 binding is associated with greater rigidity of the unbound spike RBD and with dynamics that resemble the bound state.