Noise-driven switching between expression basins in frustrated genes, locked by slow epigenetic feedback, produces robust input-dependent differentiation with logarithmic time dependence on noise strength.
Differentiation from such states has already been studied in [48] and will not be discussed here
1 Pith paper cite this work. Polarity classification is still indexing.
1
Pith paper citing it
fields
physics.bio-ph 1years
2026 1verdicts
UNVERDICTED 1representative citing papers
citing papers explorer
-
Noise-Driven Differentiation via Gene Frustration and Epigenetic Fixation
Noise-driven switching between expression basins in frustrated genes, locked by slow epigenetic feedback, produces robust input-dependent differentiation with logarithmic time dependence on noise strength.