MIST augments MIL projection layers with cross-modal gene-expression prototypes derived from spatial transcriptomics, yielding consistent gains on survival, subtyping, and biomarker tasks across 23 endpoints and 8 aggregators.
Transformer-based biomarker prediction from colorectal cancer histology: A large-scale multicentric study.Cancer cell, 41(9):1650–1661, 2023
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Bridging the Modality Bottleneck in Pathology MIL through Virtual Molecular Staining
MIST augments MIL projection layers with cross-modal gene-expression prototypes derived from spatial transcriptomics, yielding consistent gains on survival, subtyping, and biomarker tasks across 23 endpoints and 8 aggregators.