In small-budget RCTs where significance tests decide scale-up, optimal pilot sampling shifts from representative to single homogeneous subpopulation as budget shrinks.
Translating Evidence into Practice: Eligibility Criteria Fail to Eliminate Clinically Significant Differences between Real-World and Study Populations
1 Pith paper cite this work. Polarity classification is still indexing.
1
Pith paper citing it
fields
stat.ME 1years
2026 1verdicts
UNVERDICTED 1representative citing papers
citing papers explorer
-
When Representative Samples Produce Worse Outcomes: Scale-up Decisions and Testing in Small-Budget RCTs
In small-budget RCTs where significance tests decide scale-up, optimal pilot sampling shifts from representative to single homogeneous subpopulation as budget shrinks.