VibeProteinBench is a new benchmark evaluating LLMs on open-ended language-interfaced protein design across recognition, engineering, and generation, with no model showing strong performance in all areas.
Simulating 500 million years of evolution with a language model.Science, 387(6736):850–858
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Yeti is a compact tokenizer for protein structures that delivers strong codebook use, token diversity, and reconstruction while enabling from-scratch multimodal generation of plausible sequences and structures with 10x fewer parameters than ESM3.
PRIME is a five-level hierarchical equivariant graph model for proteins that uses physics-informed deterministic operators to exchange information across scales and achieves state-of-the-art results on fold classification and reaction class prediction.
citing papers explorer
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VibeProteinBench: An Evaluation Benchmark for Language-interfaced Vibe Protein Design
VibeProteinBench is a new benchmark evaluating LLMs on open-ended language-interfaced protein design across recognition, engineering, and generation, with no model showing strong performance in all areas.
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Yeti: A compact protein structure tokenizer for reconstruction and multi-modal generation
Yeti is a compact tokenizer for protein structures that delivers strong codebook use, token diversity, and reconstruction while enabling from-scratch multimodal generation of plausible sequences and structures with 10x fewer parameters than ESM3.
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PRIME: Protein Representation via Physics-Informed Multiscale Equivariant Hierarchies
PRIME is a five-level hierarchical equivariant graph model for proteins that uses physics-informed deterministic operators to exchange information across scales and achieves state-of-the-art results on fold classification and reaction class prediction.
- Atom-level Protein Representation Learning Improves Protein Structure Prediction